Lecture 29 - Randomised Controlled Trials

Question 1

Reasons for RCT?

Answer 1

reduce confounding through random group allocation

Question 2

Not good for RCT?

Answer 2

things requiring compliance from both groups e.g. high vs low fat diet; ethical dilemmas; not real world representation; expenses affecting size of sample (most important)

Question 3

Applying relative risk?

Answer 3

focuses on the proportionate benefit for people with relevant condition, rather than the whole survey pool that can underestimate benefit e.g. -3/1000 RD but 0.7 RR