Lecture 24 Pulmonary Gas Exchange Flashcards
Major components of air and compositions
N (78.09%)
O2 (20.95%)
Ar (0.93%)
CO2 (0.03%)
dalton’s law
total pressure of mixture of gasses - sum of partial pressure of gases
Boyle’s Law
at fixed temp, pressure and volume are inversely proportional
Henry’s law
@ constant temp, the amount of a given gas that dissolves in a given type and volume of liquid is directly proportional to the partial pressure of that gas in equilibrium with that liquid
partial pressure is determined by
[dissolved gas] and solubility of gas
solubility constant of O2 and partial pressure (mmHG)
0.024
150
solubility constant of CO2 and partial pressure (mmHG)
- 57
0. 21
why is the partial pressure of CO2 so much less than O2
CO2 is more soluble than O2 (greater solubility constant) so it exerts a partial pressure about 1/20th of O2
water vapor pressure
partial pressure exerted on water so it can escape from the liquid phase to the gas phase
depends on the temperature of the water (low temps = low pressure)
factors that affect the rate of gas diffusion in a fluid (5)
solubility of gas cross sectional area of fluid distance of diffusion molecular weight of gas temperature of fluid
factors that control [oxygen] in alveoli
rate of absorption of O2 in blood
rate of new O2 entry into lungs
factors that control [CO2] in alveoli
rate of CO2 excretion (increase in rate of secretion = increase in alveolar pCo2) alveolar ventilation (ventilation increase causes decrease in PCO2)
factors that determine how rapidly gas will pass through respiratory membrane
membrane thickness
membrane surface area
digestion coefficient of gas in the membrane substance
partial pressure difference between the two sides of the membrane
what is shunted blood?
venous blood that doesn’t get oxygenated when moving through lung capillaries therefore remaining deoxygenated and entering the left ventricle