Lecture 22 - Stem Cell Transplant Flashcards
1
Q
What are sources of stem cells
A
- patient BM
- patient peripheral blood
- cord blood
2
Q
What are stem cell transplants used for
A
- hematologic malignancies
- non malignant aquired BM disorders
- genetic diseases
- solid tumor chemotherapies
3
Q
What are the characteristics of stem cells
A
- CD34
- CD133
- lin
- CD117
- BCRP
4
Q
What is a syngeneic transplant
A
identical twin donor
5
Q
What is an allogenic transplant
A
siblings or matched unrelated donor
6
Q
What is an autologous transplant
A
patient is donor
7
Q
What are the steps of an autologous stem cell transplant
A
- collection
- processing
- cryopreservation
- chemotherapy
- reinfusion
