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biosci 349 virology > Lecture 20 > Flashcards

Lecture 20 Flashcards

1
Q

What are the classical definitions of life exhibited by viruses?

A

The ability to replicate
A nucleic acid genome
The ability to evolve

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2
Q

What is the complete and correct definition of a virus?

A

An obligate intracellular parasite which replicates from the assembly of individual components rather than an increase in the integrated sum of these components or division

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3
Q

What properties are common to all viruses?

A

A genome, A simple shape, the ability to reproduce, the ability to recognize and enter a specific subset of cells through interaction with one or more receptors on the surface of the cell

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4
Q

What are the differences between the evolution of viruses and the evolution of animals?

A

There is a higher mutation rate of viral genomes compared to animals ones due to the low fidelity of an RNA dep. RNA polymerase
Selection favours viruses best adapted to spread within a population during evolution

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5
Q

What is the role of quasi-species in defining viruses?

A

The term species defines similar viruses but ignores heterogeneity
Quasispecies is used to refer to the different “strains” of the virus
This can be determined by monoclonal antibody recognition RT-PCR

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6
Q

What are the methods for lab detection and analysis of viruses?

A

It can be done in whole animals
In organ cultures with one of the most successful methods using embryonated hens eggs
In lab grown tissue culture

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7
Q

What are the features of the reo family of viruses?

A

They are double stranded RNA viruses which are icosahedral and naked

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8
Q

What are the features of the Birna family of viruses?

A

Double stranded RNA viruses which are icosahedral, naked and have a segmented genome

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9
Q

What are the features of the Calici family of viruses?

A

Single stranded positive sense RNA viruses with a continuous genome and a naked icosahedral capsule

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10
Q

What are the features of the picorna family of viruses?

A

Single stranded positive sense RNA viruses with a continuous genome and a naked icosahedral capsule

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11
Q

What are the features of the flavi family of viruses

A

Single stranded positive sense RNA viruses with a continuous genome and enveloped icosahedral capsule

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12
Q

What are the features of the toga family of viruses?

A

Single stranded positive sense RNA viruses with a continuous genome and enveloped icosahedral capsule

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13
Q

What are the features of the retro family of viruses?

A

Positive sense RNA viruses with two copies of its genome and an enveloped icosahedral capsule

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14
Q

What are the features of the corona family of viruses?

A

A single stranded positive sense RNA virus with continuous genome and a enveloped helical capsule

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15
Q

What are the features of the filo family of viruses?

A

A single stranded negative sense RNA virus with a continuous genome and an enveloped helical capsule

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16
Q

What are the features of the rhabdo family of viruses?

A

A single stranded negative sense RNA virus with a continuous genome and an enveloped helical capsule

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17
Q

What are the features of the bunya family of viruses?

A

A single stranded negative sense RNA virus with a 3 segmented genome and an enveloped helical capsule

18
Q

What are the features of the orthomyxo family of viruses?

A

A single stranded negative sense RNA virus with an 8 segmented genome and an enveloped helical capsule

19
Q

What are the features of the paramyxo family of viruses?

A

A single stranded negative sense RNA virus with a continuous genome and an enveloped helical capsule

20
Q

What are the features of the arena family of viruses?

A

A single stranded negative sense RNA virus with a 2 segmented genome and an enveloped helical capsule

21
Q

What are the features of the Parvo family of viruses?

A

Non-linear DNA with a naked icosahedral capsid

22
Q

What are the features of the papova family of viruses?

A

A double stranded, circular DNA virus, with a naked icosahedral capsid

23
Q

What are the features of the adeno family of viruses?

A

A double stranded, linear DNA virus with a naked icosahedral capsid

24
Q

What are the features of the hepadna family of viruses?

A

A double stranded, circle gapped DNA virus with an enveloped icosahedral capsid

25
Q

What are the features of the herpes family of viruses?

A

A double stranded linear DNA virus with an enveloped icosahedral capsid

26
Q

What are the features of the irido family of viruses?

A

A double stranded linear DNA virus with a icosahedral capsid which can be enveloped or naked

27
Q

What are the features of the baculo family of viruses?

A

A double stranded circular DNA virus with an enveloped helical capsid

28
Q

What are the features of the pox family of viruses?

A

A double stranded linear DNA virus with a coplex enveloped capsid

29
Q

How can viruses be quantified without propagation in cells?

A

Hemagglutination and quantitative serological detection

30
Q

What are the RNA family of viruses?

A

Reo, Birna, Calci, Picorna, Flavi, Toga, Retro, Corona, Filo, Rhabdo, Bunya, Orthomyxo, Paramyxo Arena

31
Q

What are the DNA viral families?

A

Parvo, Papova, Adeno, Hepadna, Herpes, Irido, Baculo, Pox

32
Q

What are the enveloped RNA viruses?

A

Flavi, Toga, Retro, Corona, Filo, Rhabdo, Bunya, Orthomyxo, Paramyxo, Arena

33
Q

What are the naked RNA viral families?

A

Reo, Birna, Calci, Picorna

34
Q

What are the enveloped DNA viral families?

A

Hepadna, Herpes, Irido, Baculo, Pox

35
Q

What are the naked DNA viral families?

A

Parvo, Papova, Adeno

36
Q

What RNA viral families use a helical capsule?

A

Corona, Filo, Rhabdo, Bunya, Orthomyxo, Paramyxo, Arena

37
Q

What RNA viral families use an icosahedral capsule?

A

Reo, Birna, Calci, Picorna, Flavi, Toga, Retro

38
Q

What are the double stranded RNA viral families?

A

Reo and Birna

39
Q

What are the single stranded positive sense RNA viral families?

A

Calci, Picorna, Flavi, Toga, Retro, Corona

40
Q

What are the single stranded negative sense RNA viral families?

A

Filo, Rhabdo, Bunya, Orthomyxo, Paramyxo Arena

biosci 349 virology (12 decks)

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