Lecture 2: Heart Failure Flashcards

1
Q

Signs that pt HF getting worse (self-monitoring)

A

Changes in breathing
Changes in weight
New or worse swelling
Changes in ability to do everyday things

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2
Q

How much should you limit sodium intake to for hf?

A

max of 2000mg a day

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3
Q

How much fluid restriction for a stage D patient?

A

1.5-2L per day reasonable to reduce congestion

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4
Q

ADHF defintion

A

New or worsening signs or symptoms of HF that are usually caused by volume overload and/or hypo perfusion and leads to additional medical care

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5
Q

ADHF effect on curve…

A

inc afterload

Dec contractility and HR

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6
Q

What happens in ADHF

A

Most likely (excessive neurohormone release)

  1. AT2 = vasoconstriction on rigid vessels (inc after load)
  2. Aldosterone = Na/H20 retention (inc preload)
  3. NE = sympathetic stim (A+B), inc renin release, attempt to inc contractility (b), increase HR
  4. Vasopressin = inc H20 retention, inc preload
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7
Q

3 groups of ADHF

A

De novo disease = 25%
Exacerbated symptoms = 70% (stage c)
advanced or end-stage = 5% (stage d)

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8
Q

Main treatment goals

A

improve congestion and low output symptoms quickly

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9
Q

Wet =

A

excessive volume

congestion
Distended internal JVD
SOB
Pulmonary Rales
Peripheral Edema
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10
Q

Dry =

A

Not wet

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11
Q

Warm =

A

Warm extremities
Normal urine & renal function
confusion

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12
Q

Cold =

A

cold extremities
Hypotension
Bluish lips/nail beds

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13
Q

Mean arterial pressure calculation

A

((DBP X 2) + SBP ) / 3

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14
Q

What do you want to titrate MAP to when starting therapy?

A

> 65

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15
Q

How much volume do you typically remove from patient per day?

A

1-2

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16
Q

How to calculate volume

A

water weight in lbs /2.2

17
Q

Drugs given in Warm & Wet stage

A

Diuretics
Vasodilators
NTG > Nitroprusside

18
Q

Drugs given in Cold & Dry stage

A

Fluid Admin

19
Q

Drugs given in Cold & Wet stage

A

Normal BP = Vasodilators

low BP = inotropic or vasopressors

20
Q

General idea…if congested you use..

A
Diuretics
Vasodilators
Fluid Restrictions
Sodium Restriction
Compression devices to "move" fluid from tissues into vasculature

Need to reduce preload for heart to squeeze

21
Q

General idea….if low perfusion you use….

A

Inotrope
Inodilator
Pressors
Mechanical Devices

Need to stimulate “squeeze” and maintain BP

22
Q

Congestion Treatment w/ Diuretics dosing….

A

If pts already receiving loop diuretics, initial IV dose should be equal to or exceed the chronic oral daily dose and be given either Bolus or IV

23
Q

Adverse effects to consider with diuretics

A
Hypokalemia
Hypomagnesemia
Uric Acid
Resistance
Reflex inc in neurohormones
24
Q

Why might Diuretics be ineffective in ADHF?

A

Compensatory inc in RAAS leading to fluid retention

Diuretic resistance due to distal tubule hypertrophy

pts w/ renal insufficiency or low albumin req higher doses

25
If pt doesn't respond to diuretics and congestion doesn't improve, you can try to....
Restriction sodium to < 2g/d and fluids < 2l/day inc dose of loop to max bolus dose change to continuous IV add second diuretic ultrafiltration or Vasodilators
26
Role for Vasodilators
Can release symptoms of dyspnea NTG > nitroprusside
27
Low perfusion treatments - inotropes....
Short term continuous IV inotrope support maybe reasonable in those hospitalized pts presenting w/ significant reduced cardiac output to maintain systemic perfusion and preserve end organ perfusion
28
when giving Dobutamine or Milrinone
need to discontinue Beta-blockers
29
Milrinone preferred when....
increased pulmonary artery pressure | Need for B-blockade
30
Dobutamine preferred when...
Hypotension | Renal insufficiency
31
Cardiogenic shock
persistant hypotension and tissue hypo perfusion due to cardiac dysfunction in presence of adequate vascular volume
32
goals for Cardiogenic Shock
Maintain arterial pressure ( > 65) adequate for tissue perfusion 1st line = pressers Norepie tends to be more balanced, Dopamine good ton too
33
when is Norepi preferred over dopamine>
if high HR or arrhythmia concern