Lecture 2- Cells And Tissues. Flashcards
Where is the apical or free surface?
The top of the cells.
Name a microfilment.
Actin.
What is the purpose of actin?
For strength, alter cell shape, line cytoplasm to membrane, toe cells together, muscle contraction.
Name the intermediate filament
Keratin
What is the purpose of keratin?
Strength, to move materials through the cytoplasm.
What proteins bind the tight functions?
Claudin and occludin.
What is the function of the tight junction?
To be electrically tight and not let any molecules pass through. To maintain polarity.
Where in the cell is the tight junction located?
On the lateral side above the adherents junction.
Where can the tight junction be found?
In the stomach, intestines, bladder.
What protein fills the gap of the adherens junction?
Cadherin
What proteins bind the cadherin to the plaque in the adherens junction?
Catenins bind to actin that binds to the plaque.
Where is the adherens junction located in a cell?
Below the tight junction and above the gap junction on the lateral side.
What protein fills the gap in Desmosome junctions?
Cadherin
In desmosome junctions what does the cadherin bind to?
Keratin/ plaque
Where are desmosome junctions located?
On the lateral side below the gap junction and above the basement membrane.
Where can desmosome junctions be found?
In skin and cardiac cells.
What do the function of the gap junction?
Communication channel, allow small molecules to pass through.
How many Connexin proteins make up one Connexion in the gap junction?
6
How many connexons make up one channel in the gap junction?
2
Where are gap junctions located in the cell?
On the lateral side below adherens and above desmosomes.
What fills the gap of a hemidesmosome junction?
Integrin
What does integrin link to in a hemidesmosome?
To the top plague/keratin and the bottom laminin to the basement membrane.
Where about in the cell is the hemidesmosome junction located?
On the basal side attached to the basement membrane.
What are the two parts of the basement membrane?
The basal lamina and the reticular lamina.
Where is the basement membrane located within a cell?
Between the epithelium and the connective tissue.
What does epithelial tissue contain?
Nerves but no blood vessels.
What is the function of the basement membrane?
To act as a barrier and filter substances in the kidneys.