Lecture 2- Ageing and its effect on body system Flashcards
ageing and the lower airway
- Lung and chest wall compliance decrease with advancing age
- TLC, FVC, FEV1 and VC are all reduced as people age
why do
- TLC, FVC, FEV1 and VC reduced as people age
- These changes occur due to reduction in elastic support of the airways and leads to increased collapsibility of alveoli and terminal conducting airways
common post-operative complications to the lower airway in the elderly
- Atelectasis, PE and pneumonia are common post-operative complications in the elderly
- These complications are increase in smokers, pts with chronic chest disease and those undergoing abdominal and thoracic surgery
ageing and the upper airway
Loss of elastic tissue around the oropharynx
- Can lead to collapse of the upper airway
- Sleep or sedative states may result in partial or complete obstruction of the airway
- Also made worse by:
- Obesity
- Lying flat
- Sleep apnoea
- Smoking
- Opiate analgesic
Ageing and the skin
- Reduction in elasticity
- Thin skin and fragile subcutaneous blood vessels
- Therefore pts bruise easily
- Achieving and securing venous access can be difficult
Drugs to be careful with in elderly
- Steroids- thins skins
- Warfarin- blood thinners
- Aspirin (platelet levels)
- Statins
Ageing and the cardiovascular system
- Large and medium sized vessels become less compliant with age
- This results in raised systemic vascular resistance and hypertension, which in turn may lead to left ventricular strain and left ventricular hypertrophy
- aortic stenosis can also causes LVH
ECG changes
- Cardiac conducting cells decrease in number making heart block, ectopic beats, arrhythmia and AF more prevalent
why do patients with AF suffer a reduced CO of about 30%
Since atrial contraction contributes approx. one third of the volume towards normal ventricular filling
CO falls by
3% per decade which is due to reduced stroke volume and ventricular contractility
CVS changes and IV anaesthesia
Reduction in CO with age increases the arm-brain circulation time for drugs (delay between injecting person with drug and it working)and means IV anaesthesia is achieved more slowly with reduced doses of anaesthetic agents
ageing and the renal system
- GFR decreases by 1% per year over the age of 20 years due to a progressive loss of renal cortical glomeruli
- A reduction in renal perfusion secondary to reduced CO and atheromatous vascular disease leads to a decline in renal function
Other factors which effect the renal system…
- Diabetes mellitus more common in elderly
- Use of nephrotoxic drugs such as NSAIDS and ACEi are increasingly common
- Urinary symptoms due to obstruction in males can leads to obstructive nephropathy and dehydration is common in the older patients esp during illness
ageing and the CNS
- Cerebrovascular disease is common in the elderly secondary to diffuse atherosclerosis and hypertension
- Neuronal density is reduced by 30% by the age of 80
ageing and endocrine and metabolic effects
- Basal metabolic rate falls by 1% per year after the age of 30
- Fall in metabolic activity and reduced muscle mass may cause impaired thermoregulatory control
Clinical relevance of normal ageing
- Normal ageing has effects on all the major body systems and clinical management of older pts has to take normal ageing into account
- This includes impact on prescribing and anaesthesia, recovery time from operations, increases rate of post off complications, susceptibility to side effects from medications, appropriate moving and handling and general care
- Older pts are far more likely to have serious chronic conditions and co morbidities- a linear approach focussing on just one body system is not fit for purpose
Dementia
- Increasingly common condition
- Progressive
- Not just related to memory loss
- Dyspraxia
Diagnosis of dementia
- Comprehensive assessment
- Hx (history from pt and carer), Ex (exam), cognitive and Mini mental State Examination
- Blood tests
- To rule out reversible causes of confusion
- Imaging
Care plan for dementia
- Advance care planning
- Palliative care services
Which part of the brain involved in recognising objects
- Optic nerve
- Occipital- visual processing
- Temporal lobe- memory
Malnutrition in older age
At risk of being malnourished or already malnourished