Lecture 2 Flashcards

1
Q

What are the 2 types of dermatitis?

A
  1. contact dermatiti

2. Atopic Eczema

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2
Q

What are the four things that may cause atopic eczema?

A
  1. seasonal
  2. pets
  3. drugs
  4. food
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3
Q

Explain the presentation of dermatitis?

A
  • Pruritic rash, erythematous
    􏰁- May become confluent to form a wide area of rash,
  • Urticaria
    􏰁- Predominantly flexor surfaces
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4
Q

What are the common complications of eczema?

A

Scratching with leads to bleeding and therefore infection

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5
Q

Treatment of eczema?

A
  • The cornerstone is keeping the skin and lesions
    moisturised
    􏰁- Oral antihistamines if severe pruritus
  • 􏰁Topical ointments: corticosteroids
  • 􏰁Short doses of oral corticosteroids in severe cases– ——— Phototherapy (UVB)
    􏰁- Antibiotics if infected
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6
Q

Phototherapy (UVB) as a form of treatment for eczema?

A

Not suitable for everybody, ultraviolet B is used
which decreases the inflammation and help skin to
created new cells and fight against bacteria. may
take a few months to resolve

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7
Q

What is psoriasis?

A
Common, chronic, scaly, non-contagious red plaques which also affects nails and joints. Psoriasis causes scaley white
or silver patches of skin, 
specifically on extensor 
surfaces of the body. No allergic
reaction
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8
Q

What are the causes of psoriasis?

A
  • Not fully understood
    􏰀- Not allergic
  • 􏰀Primarily a disorder of excessive growth and reproduction of skin cells due to immune system over activation (increased turnover of the skin cells)
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9
Q

What is the skin presentation of psoriasis?

A
  • Causes red, scaly patches to appear on the skin
    􏰁- The scaly patches, called psoriatic plaques, are areas of inflammation and excessive skin production
  • 􏰁Skin rapidly accumulates at these sites and takes on a silvery- white appearance
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10
Q

Most common sites that plaques appear in psoriasis?

A
  • 􏰁Plaques frequently occur on the elbows, knees (extensor surfaces) and scalp, but can affect any area including nails and genitals
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11
Q

What is the joint presentation of a patient with psoriasis?

A
  • Psoriatic arthritis
    􏰁- Joints (when involved) can be painful and appear swollen, hot, and red
    􏰁- When swelling in the finger is severe, entire digits become swollen, and are often called “sausage digits” (dactylitis)
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12
Q

What is the cause of petechia, purpura and ecchymosis?

A
  • occur due to extravascularisation = blood
    under the skin, petechia less than 3mm, may
    form bigger lesions called purpura less than 1 cm.
  • bleeding under the skin in large areas is
    ecchymosis. Lupus, systemic infections can
    cause these.
  • Ecchymosis is from coagulopathies
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13
Q

What is a naevus?

A

Very large or even small pigmented areas of the skin,

accumulation of melanocytes, usually benign

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14
Q

Spider angiomas (a form of naevus) occur due to what?

A
  • abnormality of the vessels under the skin.
  • can occur in any part of the body.
  • consider systemic disease e.g. liver and thyroid disease
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15
Q

What is a Seborrheic Keratosis?

A
  • Benign, non cancerous lesions, do not appear on palms or
    soles.
  • usually symmetrical
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16
Q

What is a Actinic Keratosis?

A
  • Found on sun exposed areas,
  • pre-malignant lesion can become cancerous
  • Have to be treated quickly
17
Q

Please explain Shingles (Herpes zoster virus)?

A

Occurs due to infection of varcella zoster virus.
Varcella zoster virus hides in nerve roots. When patient is stress, the dormant virus becomes active again, causing
shingles. follows the dermatome as is hiding in nerve roots

18
Q

What are the three most common skin cancers?

A
  1. Basal cell carcinoma
  2. 􏰁Squamous cell carcinoma 􏰁
  3. Malignant melanoma
19
Q

Basal Cell Carcinoma

A
  • most common malignancy in human (80% of skin cancers)
  • 􏰀∽80% occur on the head and neck (sun-exposed regions), with the rest mainly on the trunk and lower limbs
    􏰀- begins as a small papule, and gradually becomes nodular and ulcerates centrally (“rodent ulcer”)
  • 􏰁They grow slowly and rarely metastasise
  • 􏰀Exposure to sun is the main causative factor, therefore more common in elderly
  • 􏰀Environmental and genetic factors can predispose patients
20
Q

Squamous Cell Carcinoma

A
  • Crusted, scaly, ulcerated lesions which can metastasise
  • Second most common skin cancer
    􏰀- Head and neck are the most common involved areas 􏰀􏰀- —— More common in males, usually age >45
  • 􏰀Early detection is crucial
21
Q

Most common risk factors for squamous cell carcinoma?

A
  • Sun exposure
    􏰁- Genetic, carcinogen exposure (UV radiation, X-Ray, arsenic, soot, HPV infection)
  • 􏰁Smoking (esp. lower lip) 􏰁
  • Immunosuppression
22
Q

Malignant melanoma

A
  • Malignant tumor of melanocytes which are found predominantly in skin
    􏰀- Very serious type of skin cancer, spread rapidly, deadly
    􏰀- Can be seen at any age (very rare in children
23
Q

ABCDE- Screening Moles for Possible Melanoma

A
  • Asymmetry
    􏰀- Borders: irregular, ragged, notched, or blurred
    􏰀- Colour variations, Especially red, white, and blue tones in a brown or black lesion
    􏰀- Diameter: ≥6 mm 􏰀
  • Elevation or Evolution