Lecture 2/3: History and How to Study Cognition Flashcards

1
Q

What are the historical approaches to studying cognition?

A

1) Philosophical foundations from Ancient Greece
* Rationalism and Empiricism
* The mind was studied before the birth of cognitive studies
* The Philosophers in Greece were asking a lot of questions about human thoughts.

2) The early days of psychology as an experimental science
* Structuralism and Functionalism

3) Behaviorism and then Cognitive Psychology
* Focusing on actions to accepting thought
* Studying unseen mental processes in order to understand cognition

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2
Q

What is the philosophical foundations of cognitive psychology?

A
  • Ancient Greek philosophers thought about the locus of the mind (sensations, memory) and basis of human personality.
    -They wanted to look at how human personality and characteristics were lineked to these mental processes. Why humans act and behave a certain way. They explored where was the locus of the mind.
  • Many took an analytic approach to understanding the human mind by breaking it down into ‘parts’ to study.
    - General idea accepted was to take an analytic approach to understand the mind (break down the mind into fractions).
  • Epistemology is the philosophical study of human knowledge (the nature of the limit of human knowledge)
    • Aristotle, Plato
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3
Q

What was Platos main influences?

A

1) Knowledge involves experience and reason (prior knowledge)
* Deductive reasoning: you are using scripts and understanding of how the world works to understand something.
* 1. The world is a ‘reflection of our reality’
* 2. External (bottom-up, our experiences, external world) and Internal (top-down, things we know, thoughts, feelings,perception) processing interact

1) Rationalism and the importance of a-priori knowledge
* There is an innate aspect to our mental processes and reasoning (our observations might not always reflect the real truth that is out there because we use prior knowledge)
* Observation does not always lead to certainty. (innate: we are born with the capacity to reason, innate knowledge, use prior knowledge to guide us).

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4
Q

What was Aristotle’s main influences?

A

Aristotle was into observations and what we can learn from them. He thought that observation was the center of it all.
Emphasized empiricism
* Inductive observational reasoning
* Unlike rationalism, suggests to learn from what your see
* Foundation for the importance of observation

Foundational for cognitive theories that emphasize associations (e.g., memory theories)
* Thought arise from forming associations among
observations.
* We form associations between things that we observe and the mind is nothing withou these observations. Nothing is innate in the mind, we do not start with any processes.

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5
Q

Structuralism

A

*Identify the basic elements of thought
*Learn how basic elements combine to form complex thoughts. How these basic elements can combine to from more complex thoughts. Trying to look for the lego pieces in your mind.

*Relied on introspection and self report
*People report their thoughts or observations
*What might be a problem with self report?
- they are not reliable
- some people might be good introspection and some might not be. Differences in how people understand their own mental slates.
- Emotional state can alter what they report.

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6
Q

Wilhelm Wundt

A
  • Began lab in 1879 and practiced Structuralism (looking at the basic elements of the mind)
    * “Well, Wundt you know!”
    * New science that fit in the logical framework of other sciences.
  • Wanted to identify the simplest units of the mind that he
    thought followed certain laws to create complex thoughts
    * Wanted to establish a ‘mental’ periodic table of elements
    * If he found this he could fingure out how to put them together to form our mind.
  • Used empirical introspection
    • Psychophysics
      • Way to collect experimental data
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7
Q

What is psychophysics?

A
  • Psychophysics: study basic cognitive phenomenon by linking sensory experiences to physical changes.
    • Establish a relationship between changes in a visual stimuli (physical changes) and when do people notice this change.
  • E.g., measuring the threshold for feeling the touch
    from a feather; the smallest amount of change in
    pigment to notice a difference between two colors (when does it shift from one shade of blue to another shade of blue).
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8
Q

Unit of thought

A

Our thoughts form our ability to detect changes, understand phenomenons…

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9
Q

Explain Wundt’s Empirical introspection

A

*Experimental self-observation
*Often used mental chronometry: Estimating time for a participant to perceive something (“I see it”; “I hear it”)
* Created the ‘thought meter’: People would sit in front of a pendulum that swung from left to right. When it would ring, the person has to click a button as soon as they hear the ring. They then measured how long it took for the people to say that they heard it and look at where the pendulum (how far it travelled).
* Individuals were about 1/10th of a second off = amount of time it took them to process the noise.

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10
Q

Summarizing Structuralism

A
  • Systematic observation of the elements of the mind
    * Premise: Understanding these elements will help understand more complex cognitive processes, like perception, memory and learning
  • Criticisms
    • Experimental methods were considered too subjective, relying on self report (introspection = too subjective)
    • Approaches were too simplistic (focusing on simple sensory processes) –> focusing on the simple stuff without understand why we have thoughts and how they would shift in process.
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11
Q

Functionalism

A

*Asks why the mind works
*Not interested in breaking down mental states to basic
elements
*Cognition is about serving a function and so must adapt
to current goals
* the function of why we think and how we think is essential to understand how we process information.

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12
Q

Pragmatism? Who came up with it?

A

William James and pragmatism
* Pragmatic or opposed searching for basic mental elements (focused on practical to problems).
* Believed that consciousness is personal and cannot be broken down into parts as it is constantly changing. He believed mental processes are personal and subject to change. This is why there is no point of breaking them down into parts.
* Emphasized an eclectic methodological approach to study the usefulness and variability of accessing knowledge in the real world. Because we have all these changes in mental states, there was a lot of emphasis on different methods. According to functionalist, we cannot just rely on introspection, we need to use many methods.
* Idea that you can never have the same idea twice because you will never be in the same situation.

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13
Q

What does functionalism focus on?

A

Functionalism focuses on why the mind works and the ‘usefulness of knowledge’.
- Focus on the usefulness of knowledge instead of breaking down knowledge.

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14
Q

What did functionalism contribute? and what is a critism

A

It contributed an emphasis on the adaptive functions of our mind and how we use cognitive processes based on our settings
* Context matters!
* A criticism is that it is difficult to study some of these ideas (consciousness, imagery), especially if cognition is always changing! Hard to figure out how to study these ideas, how do we gt the rootss of it?

applied research

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15
Q

Behaviorism

A
  • 1900s: Psychology is struggling to be taken seriously as a
    science. Because there was a notion that studying the mind was not as applicable to the rigor of the scientific method.
  • This resulted in a shift from studying the mind to
    behavior.
    * Focused on what can be observed (input, output). Focus on the output of what somoeone does. Focus on the idea that we are going to look at response to stimuli in the environment.
    * Behaviorism did not consider mental processes
  • Focused on animal research because there it is highly controlled
    * Assumes all species obey the same laws of behaviour. Shift from human to animal research. Behaviourist used animals because you can cut open their skulls which you cannot do with humans (ethical issues) so you can get more control with animals.
    * Emphasized the importance of controlled experiments.
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16
Q

What are the notable contributions of behaviourism?

A

1) Classical Conditioning (Pavlov)
* Learning by making associations between cue, a stimuli and the natural response
2) Instrumental Learning (Thorndike) and Operant
Conditioning (Skinner)
* Behavior is contingent on a schedule of reinforcements, rewards and punishments. Behaviours are the response to what response we are given (reward or punishment)
* Rewards encourage behaviors
* Punishment reduce behaviors
* Openrant conditioning is voluntary behaviour.

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17
Q

Why is behaviourism limited?

A

it does not account for internal mental processes and flexibility.

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18
Q

What are the problems with behaviorism?

A
  • Overestimated the scope of their explanations
    • Cannot account for complex human behavior
    • The assumption that learning was the same for all individuals and across species is false. Learning is not only different across species but also between individuals.
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19
Q

Explain an example of behaviourism’s limitations

A

Language
* Behaviorism view is that language is learned through
conditioning (operant conditioning: reward/punishment). This theory does not explain how we learn to put sentences together.
* Latent learning: learning in the absence of any conditioning (learning without being told to do so)
* see Tolman experiments in textbook for more information if needed
* Children learn to apply language rules to new situations
* Children will pluralize objects by adding an ‘s’ even if they have never seen/hear the word (mices)
* We need to refer to mental processes to explain this behavior! It does not explain how individuals are able to learn to read, memorize (need to be able to recognize the word to understand it).

		Another example: individual differences
		- If people can use mental strategies when thinking, then we need to study the mental processes.
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20
Q

The cognitive revolution

A

(1950s)
* Accepted that there are internal mental states, unlike Behaviorism but like Structuralism
* Accepted the scientific method to study these states, like
Behaviorism and other fields (e.g., math, biology)
* Came with the rise in technology and the computer that supported the view of the mind as a processor of information. The human brain is a processor, the mind anylyses information from the environment.

Cognitive phsycology:
* Humans actively process the information they receive from the environment
* The brain is the basis of mental processes
* The mind can be systematically and empirically studied

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21
Q

The view of information processing

A
  • The mind and brain can be understood as a sort of computer that processes information in the world.The brain is like a computer, performs these computations - we want to study what these computations and processes are.
  • Cognitive research focuses on describing the processes that manipulate information input from the external world to output (produce) behavior. Manipulate info that flwos from the outside world and then induces behaviour.
  • Often use flow charts to describe these computations at specific processing stages …. Model these computational stages where info is being processed and how they flow to a different computational stages
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22
Q

box and arrow flowcharts

A
  • Illustrates that processing occurs in stages
  • Waugh & Norman’s model of memory
  • The boxes represent different computational changes and arrows represent how the info flows from different computational regions.
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23
Q

Waugh and Norman’s Model of Memory

A
  • The number of words remembered decreases as the distractor task increases in length
  • You cannot rehearse information and allow that information to flow into secondary memory stage
  • Info will flow from primary memory to that forgotten stage - more info will fall out and now flow to the nectt change
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24
Q

Why do we process information?

A
  • We process information to reduce uncertainty (this is what the cognitive revolution wanted to look at).
  • Since processing information takes time, the more uncertain something is, the longer it will take it.
  • The amount of information processed is inversely related to how much we expect that information to occur. In other words, if we don’t know what to expect, we must process more.
    - The more we expect sometthing to occur, the lesss processing we need to do. But if we arent quite sure or have lots of decisions to make, we will need more cognitive processing. The more info you need to process, the more ttime it will take for you to complete the task.
    - Example: the zebra sentences. The sentence that contians more info and requires more processing because we are not certain about what the word could be.
  • In information processing, the amount of information provided by a given message is inversely proportional to the probability that that particular message will occur. More info given = less chance of it occuring.
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25
Q

What was William Hick’s experiment on information processing?

A
  • William Hick (1952)
  • The goal was to determine the relationship about how long it takes to make a decision and how much information is contained in the event.
  • Research Question: what is the relationship between choice reaction time, a proxy for processing, and the amount of information within an event?
  • Conducted a behavioral experiment measuring reaction time to detect light.
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26
Q

What were the trials for William Hick’s experiment?

A
  • Participants saw a display of 10 lamps (arranged in a circular display)
  • A lamp lit up every few seconds (Every 5 secs)
  • Participants were asked to press a button when a lamp lit up (dependent variable = how long it took them to press the button).
  • Across trials, the number of lamps that could light up:
    * For some trials: one of the ten lamps would light up. Always light up the same light so the person knew which would light up.
    * For some trials: any of the ten lamps could light up. Any could light up = random
27
Q

What were the results to William Hick’s experiment?

A
  • People were slower (higher reaction time) to detect a light if any lamp could light up than when only one lamp could light up.
  • Response time increased when there were more options/possibilities. More possibilitiess = less certain about what will happen.
  • Reaction time to press the button (dependent variable) in response to a light increased as the number of lamp alternatives (content) increased
    ** Hick’s Law: **A mathematical equation to show that the more information contained in a signal, the longer it takes to make a response to this signal.
28
Q

What does William Hick’s findings mean for our every day life

A
  • The greater the number of choices (or uncertainty of choice) requires more information to process, and thus it takes longer to make a decision
    • Why it takes so long to choose a movie on Netflix (so many options)
    • Why we have problem with long to-do lists (what do I do next?)
29
Q

Decision Fatigue

A

*Making decisions taxes cognitive processing and we have a limited amount of cognitive processing.
* Information processing has limits: we can tax our cognitive processing only to a certain degree.
* Important: Reaching decision fatigue early in the day has
consequences on our ability to make later decisions
* The more choicess you have tto pick from, the more energy you need for processing.
* Spend a lot of your cognitive resourcess to make the decision, you will find it more difficult to make a subsequent decision.

30
Q

Steve Job and decision fatigue

A

Steve Jobs wore the same outfit every day to reduce his need to make decisions early in the day. He did nott want to use any cognitive functions early in the day.
- “Your time is limited, so never wear polo shirts”.

31
Q

Webster and Thompson Experiment

A

Webster and Thompson (1953)
* Participants were air traffic controllers (the people who work here)
* They listened to two simultaneous messages: Each message had a call signal (familiar to the participants)
and unrelated words (unfamiliar to participants)
* Participants were to memorize and repeat back as much of these messages as they could remember. Call signal + 3 unrelated words.

32
Q

Webster and Thompson Experiment (result)

A
  • The air traffic controller participant could remember both call signals, but only one of the unrelated word messages for the simultaneous messages
  • This is because the familiar call signals contain ‘less information’
  • The unfamiliar unrelated word messages contain ‘more information’
  • Cognitive processing capacity is limited, so we can only process some of the information input by our senses, partly determined by familiarity/certainty.
  • The things that they are familiar with was easier for them to process. They can process both because one of the signals does not take up all their ressources. Uncertain information takes more porcessing.
33
Q

Ecological Validity

A
  • The extent to which the findings of a research study can be generalized to real-life naturalistic settings. We need to make sure that the studies explain behaviours. They must be generalized to our daily life.
  • Do we act the same way when doing computer experiments as we do in the real world?
  • Traditional laboratory approaches that try to control for confounding variables do not appreciate the complexity of cognition
    • Highly controlled, often artificial stimuli. We want it in its purest form.
    • Remembering an array of lights
    • Remembering a list of unrelated words
  • Removing confounding variables to understand principles of cognition
    in its ‘pure form’ raises the question: is there any pure form, really?
    • Consider how our context affects cognition
    • Do you think the same on a grey and a sunny day
    • Addressed in lectures to follow …
34
Q

Lecture summary

A
  • History behind cognition as a scientific study
    • Greece – Structuralism/Functionalism – Behaviourism - Cognition
  • The basic assumption of cognition research is information processing
    • We select information from our environment to process so we can reduce
      uncertainty
  • The goal of cognitive research is to understand the computations made
    on information as a sequences of operations
    • Often represented in flowcharts
    • But we must be mindful of ecological validity
35
Q

What are the assumptions of cognitive research?

A
  1. Mental processes exist
  2. Mental processes can be studied scientifically
    * Need to use rigorous experimentation.
    * We can study them objectively with quantifiable methods
  3. We are active information processors
    * We are active agents that manipulate incoming information to produce behaviors
    * We do not only passively respond to information (Behaviorism)
    * We do not engage passively. We process info in the environment and relate it to what we know. We use our mind to change and direct actions.
  4. The basis of mental processes is the brain.
    • thinking is the productt of neural activity in the brain.
36
Q

What is the mind body problem?

A
  • The mind-body problem comes from trying to answer the following question: How are mental events related to or caused by physical mechanisms in the body (brain)?
    The two most common answers to this problem are:
  • Dualism: the mind and brain are separate entities that are equally important. They are fundamentally distinct substances but they interact in some way.
  • Monism: the mind and brain are the same; Only one entity exists. There is no division between mental and physical processes. What that entity is can vary (based on different monist theories).
37
Q

Dualism - interactionism

A
  • The strongest form of dualism is interactionism.
  • The mind and brain interact to induce events in each other. The mind is immaterial and the brain is a physical object. These two substances can interact with each other.
    → Mind can affect body (e.g., thinking alters brain activity)
    → Body can affect mind (e.g., hormones affect cognition)
  • Subscribes to the idea we have a ‘soul’. We have some sort of immaterial substance.
  • Rene Descartes (early 1600’s) suggested the pineal gland is this “principal seat of the soul”, full of animal spirits, and where the interaction between entities occurs. He thought that the pineal gland was where the soul interacted with the physical brain (filled with animal spirits thatt supported perception).
38
Q

Dualism = Epiphenomenalism

A
  • It is similar to interactionism as it suggest that the mind and brain are seperate entities but there is a limit in how they can inteact.
  • Mental thoughts (mind) are caused by physical events (brain), but thoughts do not affect physical events
    * One way interaction
    * Only physical can alter mind. Mind cannot alter physical.
    * The mind is a byproduct og the physical body. It is dependent on the physical brain.
  • Mental events are like steam coming off a train (Thomas Huxley)
    * The steam (mind) does not affect how the train (brain) works, even if it is a separate entity.
    * The steam is seperate from the train (seperate entity) but it comes off from the thrain, it is a byproduct. However, it will not alter the train itself.
39
Q

Example of epiphenomenalism

A

Mental thoughts are the result of me having a physicla response to the hot pot. Me thinking the pot is hot will not cause me to pull my hand away, it is the actual physical response of the pain that causes me to pull away.

40
Q

Monism

A
  • There is one basic entity that manifests as both mental and physical responses; everything can be explained by one concept. Whether we have a mental or physical response to something is just the different manifestation of the same thing.
  • Idealism: all reality is a mental construct, both physical and mental. This is the strongest monist theory. Physical reality is the result of mental processes. Mental processes are the one entity and from those we have responses.
  • Neutral Monism: the underlying nature is not mental or physical but something else, something neutral. There is something that is directing the mental or physical response.
  • Materialism: all reality is the result of physical processes. This is the most accepted view of monism (also called pragmatic materialism). Only physical matter exists. All our mental processses are the result of our physical processes. Once we understand how the brain workss, then we can understand the mind.
41
Q

Thalamus
Hypothalamus
Amygdala

A

Thalamus and Hypothalamus: involuntary responses
Amygdala: emotional responses.

42
Q

Phrenology

A
  • Brain Localization - specific brain regions in the brain do specific functions
    *Gall and Spurzheim (late 1700s)
  • Parts of the brain correspond to mental functions and personality
    * Well-used mental functions: related brain area grows (bump)
    * Under-used mental functions: related brain area shrinks (dent)
    * If a person used a mental function a lot there will be a corresponding part of your brain that will grow and protrude from your skull.
  • False assumption that the highly developed functions have larger brain areas (only size matters) , the large the region
  • Used speculation for localizing functions. Used to measure a perssons strenghts and weaknesses.

Problems with this theory:
1) It is purely based on a matter of size.
2) Precise brain locations were determined pretty arbitrairily

43
Q

Functional Specialiazation

A
  • Modern cognitive neuroscience identifies brain area or networks that supports a particular cognitive function
  • Established via Neuropsychological cases and Neuroimaging tools (examples to come in a few slides)
  • E.g., Fusiform face area responds selectively to the perception of faces
  • But some evidence it just discriminates exemplars of any category someone has expertise
    Greebles study in the textbook
    Regions in the brain that responds only when people see a face. If FFA is damaged you cannot identify faces. Other theory: Maybe this region is active when we need to discriminate between thigs we are very good at doing. Ex: car, sheep.
44
Q

Questions to keep in mind?

A
  • How functionally specialized are singular regions of the brain?
    Functional specialization - this function is dependent on this brain region. Might not be all or none . Might be a matteer of degree.
  • Can a single brain region participate in more than one function?
    It might not be just one region. Might emerge from networks of the brain. You might depend on how that spot of cortex interacts with other parts.
  • Functions might emerge from a collection of brain regions
    It is like a string of christmas lights . You need all lights to be active for it to work properly
45
Q

Methods to study brain-behavior link

A
  • Behavioral measures
    * Behavioral Experiments (voluntary responses)
    * Demonstrated with early information processing experiments
    * Psychophysiological measurements (involuntary responses = ones you are not controlling)
  • Behavioral neuroscience methods (Psyc 211)
    * Animal models
  • Cognitive neuroscience methods
    * Patient cases
    * Neuroimaging tools
46
Q

What are psychophysiological measurements

A
  • Measure activity in the peripheral nervous system (i.e., not the brain) in
    response to things that humans perceive or imagine
  • Some examples :
    * Eye movements (covered in attention and language lectures)
    * Skin conductance
47
Q

Skin Conductance

A
  • Skin conducts electricity when it sweats. Your skin is a better conductor of electricity when you sweat (which occurs when you are emotionally aroused).
  • Detect this electrical conduction to estimate an emotional arousal response
  • Test how emotional arousal impacts cognitive tasks, like attention and memory.
48
Q

Example of skin conductance

A

Example: individuals with PTSD often have problems with regulating emotions and tested them when listening to white noise (neutral, non emotional) noise vs conbat sounds.
* Three participant groups
* Veterans with PTSD, Veterans without PTSD, Control Participants

  • Two test conditions
    * White noise, Combat sounds
  • Higher skin conductance in people with PTSD when hearing combat sounds. Much higher skin conductance response for people that were in war vs controls. These sounds are still emotionally arousing for both but it is amplified when you have PTSD.
49
Q

What is a common method used in behavioral neuroscience? Name it’s srengths and weaknesses.

A

Animal studies
* Researchers will use animals to conduct behavioral experiments, lesioning the brain or collecting physiological brain measures (Psyc 211). Lesion the brain of animals and test its affect on behaviour.

Strength
* Provides a causal link between brain and behavior (cognitive research)
* Foundational discoveries about how the mind works
* E.g., the prefrontal cortex is critical for short-term memory
Weakness
* Differences in brain structure and function across species puts limits on the generalization of these findings. Limited in what we can test.
* E.g., cannot provide a full understanding of human brain

50
Q

What is a common method used in cognitive neuroscience?

A

Neuropsychological cases and neuroimaging to understand the mind-brain link.
* Study brain function by comparing the behavior of brain-injured patients to healthy control participants
* If brain injury to area X leads to impairment on specific cognitive function, then that brain area must support that function
* Follows ideas of functional specialization
* Split brain patients

51
Q

Corpus Callosum

A
  • The connection between the two hemispheres. Allows right and left hemisphere to communicate together.
  • When cut, brain hemispheres cannot communicate with each other
  • Offers the opportunity to study the separate contributions of each hemisphere to cognitive tasks
52
Q

Split Brain Patients

A

Cut the corpus callosum to stopseizures from one side to the other (epilepsy).
* Research on split brain patients examined processing differences between the two hemispheres of the brain
* The left hemisphere supports speech and language (language processing)
* The right hemisphere supports visual-spatial processing
* They support different types of conscious awareness.

53
Q

What is the classic finding of split brain cases?

A
  • Left hemisphere supports speech and language
    processing
    * Without communication, information to the right visual field (left hemisphere) can be verbally named and
    described in words
  • Right hemisphere supports visual-spatial processing
    * Without communication, information to left visual field(right hemisphere) cannot be described verbally but can be expressed via visuo-spatial processes.

Essentially, Linguitic info to the right visual field can be procesed by LH. Linguistic info to the left visual field cannot be processed, cannot say what it is but can draw it.

54
Q

What arre the neuroimaging techniques used in cognitive science?

A
  • Measures neural communication, which is a chemical and
    electrical as well as a metabolic event (i.e., uses energy)
    1. Electroencephalography (EEG) – electrical activity. Neurons send electrical activity down the axon and EEG can measure this.
    2. Functional Magnetic Resonance Imaging (fMRI) - energy
    3. Brain stimulation techniques - change
55
Q

Electroencephalography (EEG)

A
  • An active brain produces electrical activity
    • Event-related potentials (ERP)
      • Use electrodes to measure the electrical activity at certain time and position.
        • EEG provides information about activity in the brain at certain time periods
  • Example: Present learned words and look at ERPs as view a learned word thatthey remember vs have forgotten
  • EEG measures activity in a large group (millions) of neurons at certain times
  • Provides estimate of when the brain is active
    *EEG is great at figuring out when brain activity is communicating (temporal resolution). Measured million per second. Good timing information (temporal resolution); millisecond level
    Downside
    • Poor spatial resolution: where things are occuring on the brain. Not good location information (spatial resolution)
    • Need a lot of trials of the same task. Lots of things can affect ERP signals, which means a researcher needs to collect a lot experimental trials and this limits the studies you can run
56
Q

Magnetic Resonance Imaging (MRI)

A

Structural MRI
* Anatomy of the brain
* E.g., volume, location of grey matter
* Used to detect structural anomalies - tumours, diseases, brain damage
* We can look at different sizes of different lobes

Functional (f)MRI
* Information about activity in the brain
* An indirect measure as it measures blood flow and not
neural activity

57
Q

fMRI

A

Gives you information about activity in the brain at particular locations.
* Indirect measure of neural activity, it is measuring blood flow
* Active brain areas need oxygen (metabolic energy)
* A magnet detects changes in levels of oxygenated blood. When you use a certain part of your brain, there is an iinflux of oxygen that will be observed. Energy requires oxygen!
* Measure ratio of oxygenated and de- oxygenated blood flow in regions of the brain during a task. This can tell us what part of the brain is soaking up the oxygen and working hard at a task.
* Use measurements to create a spatial image of brain activity

58
Q

Example of fMRI findings

A
  • Participants viewed images of body parts or inanimate objects
  • Consistent activity in the right lateral occipitotemporal cortex when viewing body parts compared to viewing objects
  • This is evidence of a cortical selective region for processing body parts: functional specialization
59
Q

Functional Specialization and fMRI

A
  • Parahippocampal place area (PPA) for thinking about spatial layouts
  • Supplementary motor area (SMA) for performing or imagining movement

Tested people in a vegatative state: Placed them in an fMRI and ask yes or no questions.
* People in non-responsive vegetative state via brain responses.
* Using brain specialization, ask patients to respond yes/no to questions by thinking about tennis (SMA) or walking through their home (PPA) while in an MRI scanner.
- depending on what they were thinking, different brain area was activated.

60
Q

fMRI strenghts and weaknesses

A

Strengths
* Not invasive
* Provides good spatial resolution (down to mm)
* About a 1000 papers published per month (lots of replication, validation). People will be able to peer review and critique these studies,.
Weaknesses
* Does not provide good temporal resolution to determine timing of brain activity. We do not get a good idea of when brain activity is occuring.
* It is an indirect measure of neural activity: correlational (blood flow to indicate when acivity is occuring. Do not get a measure of causation).
- Assumption that increase in blood flow means more activity
* It is very noisy…
*Blood flow can be affected by many other factors - blood pressure, caffeine, ect.

61
Q

Brain stimulation

A
  • Noninvasive method of changing brain activity that
    can inhibit or increase activity (stimulate particular regions of brain)
  • A main form is Transcranial Magnetic Stimulation (TMS)
    in a focal magnetic field induces temporary change in
    brain activity
    • Placed over part of brain. Electricity is indiced into a particular field of brain. We can either stimulate or impair the region of the brain that is under the coil.
62
Q

TMS may improve memory

A
  • Tested 2 groups of subjects: one group gets one variation, other group gets complete different variation. This gave a understanding of baseline memory function.
  • Participants in the TMS group had improved scores (up to 25%) on the post-training compared to the pre-training memory test.
63
Q

TMS

A
  • Good to test causality (testing effect of temporary lesion or stimulation). Direct Causal effect
    * fMRI and EEG are correlational (associate brain activity to task)
  • But the way it works is not entirely clear
  • Stimulation techniques have broad effects on the brain, so it is hard to localize effects
    • it is not good at localizing regions of the brain so you can stimulate one particular region but it will impact other regions. It is not clear what exact region you are stimulating.
64
Q

Advances in analysis

A
  • Linking single brain areas to functions might be too simplistic (ex: brain area a is important for task a)
  • Remember these questions about functional specialization
    - Can a single brain region participate in more than one function?
    - Functions might emerge from a collection of brain regions. Functional specialization emerges from networks.
  • Many neuroimaging analysis go beyond studying brain areas in isolation and study the brain as interconnected networks
    - Functional connectivity
    - Multi—voxel pattern analysis: way of comparing patterns of activity in the entire brain when people are doing different tasks (verbal,visual..)