lecture 2

Question 1

dendritic cell

Answer 1

• phagocytic cell - swallows up foreign particles, viruses, bacteria, chunks of tissue.
• 1 out 3 antigen-presenting cell that signals to T cells to go find antigen and destroy it
• innate immune system

Question 2

Cardinal signs of inflammation

Answer 2

• reddness
• warmth
• pain
• swelling
• altered function

Question 3

acute inflammation

Answer 3

immediate response of body to injury or cell death

Question 4

Acute inflammatory response to injury

Answer 4

inflammation occurs-> mast cells degranulate -> send out chemical messengers that there is a problem-> chemotaxis interacts with lining in blood vessels -> express selectins-> creates leaky barrier (causes swelling) -> release WBC/leukocytes from blood stream > perform phagocytosis and eat bacteria

Question 5

Neutrophils

Answer 5

• penetrates tissue
• most abundant phagocytic cell in bloodstream
• don’t present antigens professionally
• eat up foreign invaders and secrete other inflammatory molecules

Question 6

chemokines

Answer 6

stimulate chemotaxis which causes WBC to move out out blood stream

Question 7

mast cells

Answer 7

degranulate (cellular process that releases molecules from granules, which are secretory vesicles found inside some cells. )

Question 8

Vasodilation

Answer 8

the process by which blood vessels widen, allowing more blood to flow through them
chemicals that trigger: selectins, integrins, chemotaxis

Question 9

Selectins

Answer 9

cell adhesion molecules on activated endothelial cells that line blood vessels nearby

Question 10

integrins

Answer 10

adhesion receptors on neutrophils activated by selectins

Question 11

chemotaxis

Answer 11

chemotactic factors at infection site recruit leukocytes (WBC)

Question 12

Immunology has two sides

Answer 12

Innate & Adaptive