Lecture 2

Question 1

Viron

Answer 1

(infectious viral particle)

Question 2

Capsid

Answer 2

(coat) protein shell that surrounds/protects the viral genome during transmission from cell to cell. Helical or icosahedral.

Question 3

Envelope

Answer 3

Host cell and virus derived lipid bilayer (viral membrane)

Question 4

Nucleocapsid

Answer 4

The assemblage of nucleic acid and protein in a viron (has a lipid bilayer)

Question 5

Subunit

Answer 5

single folded polypeptide chain

Question 6

Structural Unit

Answer 6

unit from which capsids are build, comprised of one or more subunits

Question 7

Structural Proteins

Answer 7

form a protective shell around viral genome, and deliver genome into new host cells.

Question 8

Why should the capsid be easily disassembled during entry/name for this state

Answer 8

Metastable state, allows for structural changes and fusion to deliver genome

Question 9

Capsid structure types

Answer 9

Helical, Icosahedral, Irregular

Question 10

(T/F) The majority of capsid structures have symmetry

Answer 10

True

Question 11

Genetic Economy

Answer 11

Use of the lipid bilayer to protect the capsid. Use of DNA as genetic material

Question 12

Helical Symmetry

Answer 12

DNA and proteins have helical structure. Allows for flexibility in nucleocapsid structure.

Question 13

Icosahedral Symmetry

Answer 13

20 identical sides that are equilateral triangle subunits. Allows formation of a simple closed shell with at least 60 identical asymmetrical subunits.

Question 14

Why do viruses use symmetry

Question 15

Different types of capsid structures

Question 16

What do virus particles contain

Question 17

Characteristics of each class of virus

Question 18

Differences between DNA dependent polymerase and RNA dependent polymerase