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Veterinary Pharmacology Test #3 > Lecture 19 > Flashcards

Lecture 19 Flashcards

1
Q

These receptors in the CRTZ induce vomiting

A

Dopamine

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2
Q

Emetics should not be used in animals that are…

A

Seizures/coma patients, patients with depressed pharyngeal reflexes, patients in shock and dyspnea, patients that ingested caustic substances, or animals that don’t normally vomit (horses and rabbits)

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3
Q

Centrally acting

A

Those acting on the CRTZ or emetic center

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4
Q

Locally acting

A

Those that act on peripheral receptors at the GI tract

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5
Q

Examples of centrally acting agents

A

Apomorphine and Xylazine (Alpha 2 agonist)

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6
Q

This is the emetic of choice in cats

A

Xylazine: alpha 2 agonist

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7
Q

This is the drug of choice to induce vomiting in dogs

A

Apomorphine

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8
Q

This drug comes as an injectable or tablet; the tablet can be dissolved in saline and put into the conjunctival sac and must be washed with sterile saline after vomiting

A

Apomorphine

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9
Q

The reversal agent for Xylazine

A

Yohimbine (Yobine®️) or Atiparmezole (Antisedan®️)

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10
Q

Antiemetics

A

Drugs that are used to prevent/control vomiting by blocking dopamine receptors, centrally in the CRTZ, emeti center, and peripherally

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11
Q

Examples of antiemetics

A

Phenothiazines and Maropitant (Cerenia®️)

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12
Q

Examples of Phenothizines

A

Chlorpromazine, Prochlorperazine

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13
Q

Trade name for Metoclopramide

A

Reglan®️

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14
Q

Metoclopramide is _____ acting and should not be used with __ _____

A

Centrally; GI blockage

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15
Q

Examples of anihistamines

A

Diphenhydramine (Benadryl®️) and Dramamine®️

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16
Q

Maropitant is an antiemetic used for…

A

Motion sickness

17
Q

Where are H2 receptors located?

A

In the stomach

18
Q

HCL is produced when…

A

H2 receptors are stimulated by histamine binding

19
Q

Where are gastric parietal cells located?

A

In the lining of the stomach

20
Q

Gastric parietal cells produce…

A

Hydrochloric acid

21
Q

Job of H2 blockers

A

To stop the production of HCL and decrease acid production

22
Q

Examples of H2 blockers

A

Cimetidine (Tagamet®️), Rahitidine (Zantac®️), and Famotidine (Pepsid®️)

23
Q

One example of proton pump inhibitors

A

Omeprazole (Prilosec®️)

24
Q

Job of Omeprazole

A

Binds to the proton pump and stops acid formation by stopping hydrogen molecules from going to the stomach

25
Q

This is the drug of choice for antidiarrheals and also is a controlled Class V drug

A

Lomotil

26
Q

Antibiotics that are used as antidiarrheals

A

Metronidazole (Flagyl®️) and Tylosin

27
Q

Examples of GI protectants

A

Sucranlfate (Carafate®️) and Bismuth subsalicylate (Pepto Bismol®️)

Veterinary Pharmacology Test #3 (6 decks)

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