Lecture 17: psychoSocial factors in SZ – Part I Flashcards
What are the psycho-social factors in SZ?
- Disengagement with treatment
- Substance use and abuse
- Suicide
- Unemployment
- Homelessness
- Poor health
- Stress
- Violence and victimization
Are medical and psychological treatments for SZ effective?
Only partially effective
Because of it’s partial effectiveness of treatment for SZ, _____ of people with SZ do not engage in treatment in a continuous way
About half
What are the reasons a person with SZ might not engage in treatment?
- Related to the disorder (symptoms prevent engagement)
- challenges of medication (people may not comply with their medication regime because of their symptoms, may not want to).
Other life factors which poses challenges for people with SZ to access treatment include:
- Disengagement from family and social support
- Substance use and abuse
- Homelessness
- Unemployment
- Legal issues (rel. to substance abuse, rel. to paying bills)
People with SZ have a higher rate of current use depending on the location. What is the % at any given time?
What is the % of life-time use?
Which location is associated with higher rate of drug use and abuse?
- 10-50% (at any given time)
- Larger cities, more economically depressed areas = more likely to use
- life-time used is 45-50% (most people will have use and abuse drugs at some point in their lives).
Most commonly used and abused are:
Alcohol and cannabis
What are Negative consequences for SZ patients who use & abuse subtances?
- Reduced engagement with treatment
- Related to increased symptoms and hospitalization
- Homelessness, violence, victimization, suicide
What is the association between cannabis and age of onset of SZ?
- Earlier age of onset (Helle, 2016)
- For those who reported cannabis use, age of 1st episode 3 years earlier than those who did not
Is there an overlapping genetic risk with SZ and drug abuse?
- Overlapping genetic risk with SZ is debated
- Related to the same increased risk for all people in the same SES, education, employment categories
- Being poor, uneducated and unemployed makes you more likely to use and abuse (more likely in SZ)
- It may cause SZ:
Some evidence for cannabis as a contributor to onset - It is a result SZ:
Those who develop SZ also more likely to abuse
The Hambrecht & hafner, (1996) study, 232 people at first episode with SZ or psychotic disorder were recruited. What was the results of the study?
- Alcohol abuse seen in ___________
- Drug abuse seen in _______________
- __________ most common drug; -combined Alcohol and drugs are _______
- Both Alcohol and drug abuse more common in ____
- Alcohol abuse seen in 24% (2x rate of controls)
- Drug abuse seen in 14% (2x rate of controls)
- Cannabis most common drug; -combined Alcohol and drugs common
- Both Alcohol and drug abuse more common in men
The Hambrecht & hafner, (1996) study where they recruited 232 people at first episode with SZ or psychotic disorder, also showed that:
- People with drug abuse had _________
- People with alcohol abuse had ________
- Combined drug and alcohol abuse _________
- People with drug abuse had earlier symptom onset and 1st admission
- People with alcohol abuse had first sign and negative symptom earlier
- Combined drug and alcohol abuse does not change the pattern (there’s no additve effect, they had had first sign and negative symptom earlier)
What is the most common self-reported reason for abuse?
“alleviation of dysphoria” – Drinking, using drugs to cope with negative feelings
Why are other reasons why drug abuse occur?
- Alienation (may not be in employment, loss of contact with others)
- Social drift (like the gen. pop having a lower SES, being unemployed, homeless).
- “Supersensitivity”:
[Possibly related to genetics of the DA system
[To drugs of abuse that affect DA system
[To stressors that then promote further abuse
The risk of suicide in SZ is ____times the rate of the general population.
4x
