Lecture 17 Flashcards

1
Q

What are some functions of the smooth muscle?

A
  • Regulating blood pressure
  • Peristalsis in the digestive system
  • Ciliary muscles in the eye
  • Pilo-erection
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2
Q

How is contraction regulated?

A
Synaptic inputs from ANS
Circulating and local hormones
Metabolites
Electrical activity of neighbouring cells
Gap junctions
Unitary
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3
Q

What are the sarcolemma pathways for regulating Ca2+

A
  1. Voltage gated calcium channels
  2. Ligand gated channels
  3. Store operated Ca2+ channels
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4
Q

How does the regulatory light chain work in controlling cross bridge cycling

A

There is an extra step for smooth muscle. When myosin is phosphorylated by myosin light chain kinase the myosin is activated. Deactivation occurs which myosin phosphatase.

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