Lecture 17 Flashcards
maltose
glucose + glucose
sucrose
glucose + fructose
lactose
glucose + galactose
Deficiency in lactase
causes lactose intolerance
Glucose and galactose are absorbed by
active transport
Fructose is absorbed by
facilitated transport
Peptide and Amino Acid Transport step 1
Proteins broken down into
smaller peptides
Peptide and Amino Acid Transport step 2
Epithelial cells secrete
peptidases to break down
larger peptides into
individual amino acids
Peptide and Amino Acid Transport step 3
Transported throughout the body via the bloodstream in order to produce energy (in
liver) or protein synthesis
lipid digestion
Emulsifying fat – making fat soluble with bile
Bile salts are
Amphipathic:
Hydrophilic AND lipophilic, like a soap or detergent
lipase
breaks down fats
Lipid Absorption and Transport step 1
absorbed as fatty acids
and monoglyceride
Lipid Absorption and Transport step 2
Reassembled into
triglycerides and packaged
as chylomicrons (a type of
lipoprotein)
lipid absorption and transport step 3
Chylomicrons are too large
to cross capillary wall …
first absorbed into lymphatic system
lipid absorption and transport step 4
Will re-enter circulation via
thoracic duct near the heart
Large Intestinal phase of digestion and absorption includes
any unabsorbed nutrients, hormones + chem messengers, soluble fibers (prebiotic), insoluble fiber (bulking agent), microbes (probiotics and other), cellular debris, excretion products from the liver
what comes from the ileum (ileocecal valve)
ileal chyme (chemical and particle rich liquid)
what happens in the large intestine (cecum + colon) step 1
the colonic epithelium absorbs water and simple ions (sodium, magnesium, potassium, calcium)
what happens in the large intestine (cecum + colon) step 2
resident microbes digest and absorb what chemicals they can (prebiotics) in a process called fermentation. Short chain fatty acids are produced as end products of fermentation
what happens in the large intestine (cecum + colon) step 3
resident microbes produce some vitamins (K, some B) as by products of their metabolism. Some end products can have hormone-like activity
what happens in the large intestine (cecum + colon) step 4
resident microbes produce gases during their digestion and consumption of ileal chyme. (methane, carbon dioxide, hydrogen sulfide)
what happens in the large intestine (cecum + colon) step 5
newly arriving live microbes (probiotic or other) seek to get a foothold in the microbial ecosystem and multiply
hedonic hunger or eating
“the drive to eat to obtain pleasure in the
absence of an energy deficit.”
homeostatic hunger or eating
increased motivation to eat following depletion of energy stores