lecture Flashcards
Is the cell membrane a fluid or a solid?
fluid
describe the cell membrane
contains the lipid bilayer
covers the cell
also referred to as the plasma membrane
How thick is the plasma membrane
7-10 nm thick
The cell membrane is composed of how many percentage of Protein, Carbohydrates, and Lipids?
55 protein
3 carbohydrate
42 Lipid
Explain the amphipathic structure of a phospholipid
Contains a hydrophilic glycerol head facing the Intracellular membrane and extracellular
and two fatty acid tails
Fluid inside of a cell
Intracellular fluid
Process of attaching sugars
Post-translational modification found in mitosis and meiosis
Glycosylation
Two types of Glycosylation
N-Glycosylation
O-Glycosylation
Interstitial: Supports, surrounds, the cell: 75 percent of fluid in the body
Intravascular: Blood plasma : 25 percent of the body
Transmembrane fluid: synovial fluid, ocular fluid, Cerebrospinal fluid (backbone fluid)
Extracellular fluid
OLIGOSACCHARIDES LINKED TO THE NITROGEN ATOM ON AN ASPARAGINE
N-Glycosylation
OLIGOSACCHARIDES ARE LINKED TO OXYGEN L, TYPICALLY ON SERINE OR THREONINE OR THREONINE RESIDUE
O-Glycosylation
Integral funvtiom of the cell membrane and cell walls
Structure
IMPORTANT ROLES OF GLYCOPROTEINS
CELL MEMBRANES
TISSUE STRENGTH
PLANT GRAVITY RESISTANCE (It’s why despite how tall a plant is, it doesn’t topple over)
IMMUNE RESPONSE IN BLOOD VESSELS
BRAIN FUNCTION
BLOOD CLOTTING
BLOOD TYPE IDENTIFICATION
REPRODUCTION
MUCUS PRODUCTION
IMMUNEE SYSTEM SUPPORT
SKIN HEALTH
This protein is Embedded: found deeply in the phospholipid bilayer
Spanned: it is found in the entire cell membrane
Embedded: found deeply in the phospholipid bilayer
Spanned: it is found in the entire cell membrane
Type of integral proteins
Alpha Helix
Helical bundle
Beta barrel
Example of beta barrel
Small ions
Chain sa fatty acid
OmpA - small iron channel
OmpT - Protease
NalP - auto transporter
FadL - long fatty acid chain transporter
PhoE - defusion pore
ScrY - Sucrose specific porin
OmpiA - Phospholipase (Integral protein)
Alpha helix sample
Myoglobin
Hemoglobin
Present in one side
Hormone receptors
Cell membrane antigens
Does not like to stick inside the membrane. It’s just outside. repeat: it’s only found in ONE side.
Only one percent of the membrane is Peripheral
They are transport assistants to integral protein.
Peripheral protein
Protein for extracellular electron pathway
Cytochrome C
An electron transfer shuttle (The bus that electron rides on)
Cupredoxins
Iron sulfur protein.
Also an electron transfer in photosynthetic bacteria
High Potential Iron Protein
HIPIPPPP
Receives an electron coming from NADPH (NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE) In the Calvin cycle
Adrenodoxin Reductase
example of how proteins work as a channel for Ions:
Bioelectric- Voltage-gated
Ligand-Gated : Opens and closes because a binding has occurs
Macromolecules in cells include
Proteins
Nucleic Acids
Carbohydrates
Lipids