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MWU Winter 2023/2024 Block 3 > Lecture 16: Posterior column-medial lemniscus system (PCMLS) > Flashcards

Lecture 16: Posterior column-medial lemniscus system (PCMLS) Flashcards

1
Q

Ascending pathways: somatosensation
Posterior column-medial lemniscus system (PCMLS)
Green
- BLANK touch
- BLANK sense
- BLANK

Anterolateral system (ALS)
Yellow
- BLANK
- BLANK
- BLANK

Descending pathway: somatomotor
Corticospinal tract (CST)
Grey
-BLANK

A

Ascending pathways: somatosensation
Posterior column-medial lemniscus system (PCMLS)
GREEN
- discriminative touch
- vibratory sense
- proprioception

Anterolateral system (ALS)
YELLOW
- pain
- temperature
- non-discriminative (crude) touch

Descending pathway: somatomotor
Corticospinal tract (CST)
GREY
- fine movements of the distal extremities

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2
Q

Posterior column-medial lemniscus system (PCMLS)_

Function: convey the following BLANK modalities from the BLANK to the primary BLANK cortex
- BLANK touch: the ability to BLANK (cutaneous mechanoreceptors)
- BLANK: ability to perceive body position, movement (deep mechanoreceptors)
- vibratory sense: ability to perceive BLANK (cutaneous mechanoreceptors)

A

Function: convey the following somatosensory modalities from the body wall to the primary somatosensory cortex
- discriminative touch: the ability to precisely localize tactile stimuli on the skin surface (cutaneous mechanoreceptors)
- conscious proprioception: ability to perceive body position, movement (deep mechanoreceptors)
- vibratory sense: ability to perceive oscillatory stimuli on the skin surface (cutaneous mechanoreceptors)

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3
Q

Neuron 2
- cell body in BLANK or BLANK
- axon decussates: ascends
in BLANK
- synapse in BLANK

A
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4
Q

Neuron 1
- peripheral process with receptive
ending (peripheral cutaneous nerve)
- cell body in BLANK
- central processes form BLANK or BLANK
- synapse in caudal medullaBLANK

A
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5
Q

Neuron 3
- cell body in BLANK
- axon ascends in BLANK
- synapse in BLANK

A
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6
Q
A
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7
Q
A
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8
Q

AB

A
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9
Q

Key features of primary sensory neurons in PCMLS pathway:
▪ BLANK morphology
▪ BLANK diameter and BLANK myelinated
▪ BLANK conducting fibers

A

Key features of primary sensory neurons in PCMLS pathway:
▪ pseudounipolar morphology
▪ large diameter and heavily myelinated
▪ rapidly conducting fibers

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10
Q

PCMLS_primary sensory neuron

cell body in BLANK
- central process enters spinal cord in the BLANK of the posterior root entry zone

Branches:
- synapse in spinal cord at, above, or below the level of BLANK (ascend and descend
in BLANK to participate in spinal BLANK)
- ascend in BLANK posterior BLANK in the BLANK or BLANK depending on origin of stimulus

A

cell body in PRG
- central process enters spinal cord in the medial division of the posterior root entry zone

Branches:
- synapse in spinal cord at, above, or below the level of entry (ascend and descend
in fasciculus proprius to participate in spinal reflexes)
- ascend in ipsilateral posterior funiculus in the fasciculus gracilis or fasciculus cuneatus depending on origin of stimulus

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11
Q

fasciculus gracilis: tactile sensation from BLANK

fasciculus cuneatus: tactile sensation from BLANK

A

fasciculus gracilis: tactile sensation from below T6 dermatome (lower extremity , pelvis, abdomen, lower thorax)

fasciculus cuneatus: tactile sensation from T6 and above (upper thorax, upper extremity , neck)

DERMATOME!!!

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12
Q

PCMLS_neuron 2

  • cell body in gracile or cuneate
    nucleus in BLANK
  • axon decussates and ascends in
    BLANK
  • synapses in BLANK nucleus of BLANK
A
  • cell body in gracile or cuneate
    nucleus in caudal medulla
  • axon decussates and ascends in
    contralateral medial lemniscus
  • synapses in VPL nucleus of thalamus
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13
Q

PCMLS_neuron 3

  • cell body in BLANK
  • axon in posterior limb of BLANK
  • synapses in BLANK
A
  • cell body in VPL
  • axon in posterior limb of internal capsule
  • synapses in primary somatosensory cortex (S1)
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14
Q

Primary somatosensory cortex (S1)

A
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15
Q

Reitteration Pathways

  • touch sensation from the right lower extremity enters the BLANK of the spinal cord via the BLANK and ascends in the ipsilateral BLANK
  • touch sensation from the right upper extremity enters the BLANK of the spinal cord via the BLANK and ascends in the ipsilateral BLANK
A
  • touch sensation from the right lower extremity enters the right
    side     of the spinal cord via the medial division of the posterior root entry zone and ascends in the ipsilateral fasciculus gracilis
  • touch sensation from the right upper extremity enters the right
    side     of the spinal cord via the medial division of the posterior
    root entry zone     and ascends in the ipsilateral fasciculus
    cuneatus
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16
Q

Posterior Colum Medial Lemniscus Systemns

A
17
Q

Posterior Colum Medial Lemniscus Systemns

PONS

A
18
Q

Posterior Colum Medial Lemniscus Systemns

MIDBRAIN

A
19
Q

Posterior Colum Medial Lemniscus Systemns

thalamus and internal capsule

A
20
Q
A
21
Q
A
22
Q
A
23
Q
A

MWU Winter 2023/2024 Block 3 (7 decks)

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