Lecture 14 - Membrane Structure (Ch 11) Flashcards

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1
Q

Describe the tail part of a lipid

A

uncharged, nonpolar, hydrophobic

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2
Q

In osmosis, how does water move through concentration gradients?

A

Water moves from areas of low to high solute concentrations

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3
Q

Cholesterol is ideal for what situation?

A

When temperatures drop, cholesterol helps phospholipids to be properly spaced; they also prevent being too fluid in room temps

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4
Q

Peripheral proteins are found on either layer of the membrane , T/F?

A

True- but one, not both for each one

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5
Q

Integral proteins typically hold what job

A

They can be transporters or channels

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6
Q

Glucose molecules are too big and polar to cross the cell membrane by themselves, true or false?

A

True; they rely on integral proteins

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7
Q

Glycoproteins and glycolipids allow you to

A

recognize and signal other cells!

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8
Q

Which glycoprotein is found by HIV to infect cells? but usally this glycoprotein is for..

A

CD4; cell immunity

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9
Q

The most abundant phospholipid in the membrane is

A

phosphatidylcholine

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10
Q

Galactocerebroside is a typie of ___

A

glycolipid

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11
Q

What is an example of hydrophilic molecules attracting water molecules

A

acetone

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12
Q

What is an example of hydrophobic molecules avoiding water? Describe the process

A

2 methylpropane; water makes a cage around 2 methylpropane to max out h bonding duudeee

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13
Q

How do phospholipids repair themselves?

A

By spontaneous rearrangment of phospholipids, you can heal the membrane if it tears or holes

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14
Q

Which conformation of the membrane is energetically favorable?

A

the ball shape (enclosed) comes out on TOP compared to the flat one

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15
Q

What has the highest influence of membrane curvature?

A

The lipid hydrophilic head

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16
Q

What type of movement barely happens in the bilayer?

A

Flipflopping lipdis

17
Q

What movements happen usually in bilayers?

A

Flexion, rotation, and lateral diffusion

18
Q

How do lower temperatures affect phospholipid compositions in MICROBES?

A

Low temp makes the phospholipids have more double bonds and shorter tails (more fluid)

19
Q

How do higher temperatures affect phospholipid compositions in MICROBES?

A

High temp makes phospholipids have single bonds and longer tails (less fluid)

20
Q

-% of membrane lipid content is cholesterol; where does it fit in?

A

20%; in spaces left by unsaturated fats’ kinks

21
Q

Why is important to have a fluid membrane mosiic modelas dadalsdkjalsd?

A

For cell signaling, cell division, fusing membranes, and distributing proteins after they are made

22
Q

Where does membrane synthesis begin? On which surface?

A

the ER; on the cytosolic side

23
Q

Which ones random: flippase or scramblase?

A

scramblase

24
Q

What are the steps to making a membrane?

A

Phospholipds areDEPOSITED into cytosolic side of ER, then FLIPPED to noncytosol side using enzymes

25
Q

Which lipids do flippases move and where are they going? where are these enzymes working?

A

P.ethylalanine and p.serine move from inner to outer lelaflet; they work with incoming lipids from the ER in the golgi app

26
Q

Plasma membranes range from__ to __ nm in thickness.

A

5-10 nm

27
Q

What plasmamembrane movement is NOT spontaneous; what does it mean to be spontensous vs random?

A

moving between the bilayers; spont = no help (energy assistance) and random -= no order

28
Q

Which lipids can I find in the cytosolic side (inner leaflet)

A

Phos insitol (PI) , phosphotidylserine (PS) and phos ethanolamine (PE) get moved here

29
Q

What lipids can I find on the extracellular (outer leaflet) side of the membrane?

A

Phos choline (PC), glycolipids (GL), and sphingomyelin (SM)