Lecture 14 Flashcards
Neutrophils
early stages of infection (Phagocytic)
Basophils
Release histamine; work in allergic responses
Eosinophils
Toxic against parasites and helminths (Phagocytic)
Monocytes
Mature in macrophages in tissues where they’re phagocytic
Dendritic cells
Found in the skin, mucous membranes, and thymus (Phagocytic)
Lymphocytes
T cells, B cells, & NK cells; play a role in adaptive immunity
Innate immunity
Defenses against any pathogen; rapid, present at birth
Adaptive immunity
Immunity or resistance to a specific pathogen; slower to respond, has memory component
Phagocytosis
Microbes are ingested into the cell
Classical pathway
Antibodies bind to antigens, activating C1
Alternative pathway
C3 present in the blood combines with factors B, D, & P on microbe surface
Lectin pathway
Macrophages ingest pathogens, releasing cytokines that stimulate lectin production in the liver
Cytolysis
proteins create a membrane attack complex (MAC)
Opsonization
attachment of a phagocyte to a microbe
Inflammation
bind to mast cells, releasing histamine