Lecture 13- The Somatosensory System Flashcards
What does the somatosensory system consist of?
- Somatosensory receptors & neurons
- Afferent axons and neurons that form the somatosensory pathways
- Neurons of somatosensory cortex
What are the three types of sensory receptors according to how they are distributed throughout the body?
- Exteroceptive: external skin contact, temperature
- Proprioceptive: body, limb, joint position
- Enteroceptive: internal organ status (eg bladder fullness, blood gases), maintaining homeostasis
What does the somatosensory system do?
- It provides the brain with information about the state of the body, and about some aspects of the external environment
- This information is used to help guide behaviour and to maintain homeostatic function
What is the other way the brain receives important sensory information?
Special senses (vision, hearing, balance, smell, taste)
What are the 4 main features of stimulus that is encoded in information from somatosensory receptors?
- Modality: receptor specificity (what ‘type’ of information), eg touch and temperature are reported by different receptors and signaled separately (the “labelled line”)
- Intensity: the frequency of action potential firing in a sensory axon, and the number of activated axons encodes the intensity (strength) of the stimulus
- Location: the somatotopic mapping of receptors in specific areas allows the location (site) of the stimulus to be known
- Duration: the beginning/end and pattern of action potential firing can encode the start and end of a stimulus
How is stimulus intensity encoded?
The bigger the stimulus the higher the frequency of action potential firing (more likely to reach threshold for AP)
What is signal transduction?
The process of taking a stimulus and converting it into action potentials. Action potentials in the CNS then result in sensation (brain)
What is required for signal transduction to occur?
Need a receptor specific to the stimulus
What are the three broad types of somatosensory receptors in the skin (Exteroceptive)?
- Mechanoreceptors: touch, pressure
- Thermoreceptors: temperature
- Nociceptors: noxious stimuli (triggering pain sensation)
What are the two types of skin?
- Hairy= majority
- Hairless= found on palms of hands + soles of feet, lips and fingertips
What is the general mechanism for which mechanoreceptors in the skin work?
- Have channels in membrane, when pressure is applied to membrane of receptor it distorts the protein, allowing for the entrance of positive ions into the cells (channel opens).
- This mechanical deformation results in a receptor potential and then if this great enough (threshold) an action potential will result in signals being sent to the brain
What are the 5 types of skin mechanoreceptors + their general functions?
-Meissner’s corpuscles: Glabrous skin (mostly), pressure, dynamic,
rapidly adapting, low threshold. Very light touch will result in the perception of touch.
-Pacinian corpuscles : Subcutaneous (all skin), interosseous, viscera,
deep pressure, vibration, dynamic, rapidly adapting, low threshold. Light touch will not activate these.
- Merkel’s discs: All skin, static pressure, convey info about shape & texture of objects, slowly adapting, low threshold
- Ruffini endings: All skin, deeper pressure & stretch, slow adapting, low threshold
- Hair units: Hairy skin, hair displacement (due to breeze or touch= compute info about enviroment), low threshold, rapidly adapting
In terms of the features of the skin’s mechanoreceptors what does rapidly adapting versus slow adapting mean?
- Rapidly adapting = Stop firing action potentials within a short period of stimulus onset
- Slowly adapting= Firing action potentials throughout the entire stimulus, only stop when the stimulus itself stops
What are the skins thermoreceptors and nociceptors like? How are they typically classified?
-Free nerve endings in all skin types
-Typically classified by type of axon:
Myelinated axons= Temperature (usually change in temp)
Unmyelinated or thinly myelinated axons= Nociceptors (respond to mechanical, thermal, or chemical stimuli)
What are Proprioceptors? What are they used for?
-Mechanoreceptors in muscles and tendons that provide information
relating to change in muscle length (muscle spindles) & force (Golgi tendon organ)
-Used by CNS to sense limb movement & limb/body position
-Crucial for stretch reflex