Lecture 13 - MRI Flashcards
MRI
magnetic resonance imaging
How do MRIs work?
Based on protons emitting radio waves in the presence of strong magnetic fields and pulses of radiofrequency energy
Benefits of MRI
No exposure to ionizing radiation
No significant biologic effects
Each set of images is from a series of radiofrequency pulses and variations in the magnetic field, called…
Pulse Sequence
Describe an MRI Scanner
Scanners are like a larger, thicker CT scanner
Some scanners are open at the sides or are vertical, which may assist claustrophobic patients.
Difference between open and closed scanners
Open scanners may be slower and not have the same image quality as closed scanners
How are scanners described?
Scanners described by the strength of their primary magnet
Typical magnet strength
1.5 Tesla
How are images produced?
Primary magnetic field is modified by additional fields, resulting in varied magnetic field strengths or gradients – these are used to produce the images
The fields affect the spin of hydrogen protons in the patient
Radiofrequency pulses are applied to these protons which give off radio waves that are detected by receiver coils (antennas).
Output from the coils creates the images.
Gradient fields and radio pulses chosen for each set of images (pulse sequence) creates the images but also the different appearance of tissues on the images
Most common pulse sequences
T1 or T2 spin echo T1 or T2 fast spin echo T1 or T2 gradient echo FLAIR sequence STIR sequence
Sequences are usually referred to as
T1 or T2 sequences (or T1-weighted or T2-weighted) sequences
called the longitudinal relaxation time and is the time it takes for the tissue to recover to its longitudinal state before the radiofrequency pulse was given
T1
the transversal relaxation time and is the time for the tissue to regain its transverse orientation before the radiofrequency pulse was given
T2
As soon as the pulse stops…
relaxation begins and the spinning nuclei release energy that is picked up by the receiver coil and produces an image
What appears dark on a T1 image?
calcification air chronic hemorrhage acute hemorrhage water (edema, CSF)
Have low signal and appears dark on the image.
What appears bright on a T2 image?
Lipids
Subacute hemorrhage
Fluid containing protein will have high signal and be bright.
What causes tissue to have a high signal?
Contrast will cause tissue with the contrast to have high signal
What appears dark on a T2 image?
fat calcification air early subacute hemorrhage chronic subacute hemorrhage chronic hemorrhage acute hemorrhage high protein
What will appear bright on a T2 image?
Water - Edema, CSF
Why do lipid containing tissues not affect not affect high signal?
T1 and T2 sequences can suppress the signal from lipids so that lipid containing tissues do not affect high signal from adjacent high signal fluid or tissue
Most common MRI contrast
Gadolinium
How is Gadolinium administered?
IV
Intraarticularly
How does Gadolinium work?
Enters the blood stream, enhances organ parenchyma, and is excreted by the kidneys
Causes a brighter signal on T1-weighted images – since fat is already bright the images are usually fat-suppressed to enhance the effect of the contrast
What structures light up with contrast?
Structures that light up with contrast are vascular (tumors) and inflammation and are described as enhancing
Who should not receive Gadolinium?
Pts with renal insufficiency
What can patients with renal insufficiency develop after Gadolinium?
Patients with renal insufficiency should not receive gadolinium as they are at risk for developing nephrogenic systemic fibrosis – produces fibrosis of skin, eyes, joints, and internal organs.
Patients with preexisting renal disease, especially dialysis patients, are at greatest risk
What has better soft tissue resolution?
MRI
MRI>CT for soft tissue resolution.
If contrast is indicated and CT and MRI are equivalent but contrast is contraindicated, what do you use?
unenhanced MRI is usually better than unenhanced CT
What must be removed from the patient before an MRI?
Has very strong magnetic fields, so metal objects are removed from the patient
Surgically implanted or imbedded metal devices and objects may be a problem.
If motion of the device or object may be harmful, then MRI cannot be done – cerebral aneurysm repair clips, vascular clips, surgical staples
What foreign bodies can cause an issue with MRIs?
Foreign bodies, such as bullets, shrapnel, and metal in the eyes, are also a problem
Patients with pacemakers, defibrillators, pain stimulator implants, insulin pumps, other implantable drug infusion pumps, and cochlear implants cannot have MRIs – devices can be deactivated by magnetic field
MRI Safety during pregnancy
Limited data on safety during pregnancy – American College of Radiology says pregnant patients can undergo MRI at any stage of pregnancy if benefit outweighs the risk. Should not be performed electively early in pregnancy, and gadolinium is not recommended in pregnancy.
MRI safety with metal objects
Some may still have an MRI depending on the metals used, the shape of the objects, and the location involved.
Issues with MRI
Very expensive
May be difficult for some patients due to psychological reasons
May not be ideal modality for all cases –bone has little or no MRI signal so CT is better
What images can MRI provide?
Axial
Sagittal
Coronal
Just like CT
MRI is used for…
Musculoskeletal Neurologic GI Endocrine/Reproductive GU
What does a Musculoskeletal MRI evaluate?
Bone marrow Menisci Tendons Muscles Bones Osteomyelitis Spine
What is a Musculoskeletal MRI used for?
Assess for meniscal tears Ligamentous or tendon injuries Contusions Occult or stress fractures Disk disease and marrow infiltration Differentiating scarring from prior surgery from new disease