Lecture 13 - Introduction to G.I. Tract Physiology Flashcards
1
Q
What are the GI hormones?
L16 S16
A
- gastric
- CCK
- secretin
- GIP
2
Q
What is the action of gastrin where does it come from, and what factors stimulate or inhibit its secretion?
L16 S17
A
Action:
- gastric acid secretion
- mucosal growth
Origin:
-G cells of small intestine
Stimuli:
- small peptide and AA (especially F and W)
- stomach dissension
- vagal stimulation
Inhibition:
- acid from stomach
- somatostatin
3
Q
What is the action of cholecystokinin (CCK) where does it come from, and what factors stimulates its secretion?
L16 S18
A
Action:
- pancreatic enzyme secretion
- pancreatic bicarbonate secretion
- growth of exocrine pancreas
- inhibits gastric emptying
- inhibits appetite
- contraction of gallbladder
Origin:
-I cells of small intestine
Stimuli:
- small peptides or AAs
- fatty acids or monoglyceride
4
Q
What is the action of secretin where does it come from, and what factors stimulates its secretion?
L16 S19
A
Action:
- pepsin secretion
- pancreatic bicarbonate secretion
- biliary bicarbonate secretion
- growth of exocrine pancreas
- inhibits gastric acid secretion
Origin:
-S cells of small intestine
Stimulus:
-acid and fat in lumen of duodenum
5
Q
What is the action of GIP where does it come from, and what factors stimulates its secretion?
L16 S20
A
Action:
- stimulate insulin release
- inhibits gastric acid secretion
Origin:
-K cells of duodenum and jejunum
Stimuli:
-protein, fat, and carbohydrates
