Lecture 12 Flashcards
What is deflection?
deviation from a straight line (in ECG upward/downward peak/wave from baseline/isoelectric line
+ve deflection is upright
How does an ECG work?
Electrical changes (depolarisation/repolarisation) recorded via electrodes placed on limbs and chest wall and transcribed onto graph paper
How many views does an ECG provide electrical activity from?
12 separate views
Therefore if there is an abnormality in activity we can localise it to a region of the heart
What is meant by the heart being an intrinsic rhythm?
If supported by ions and energy, can beat outside our body.
What are pacemaker cells?
Specialised cardiac myocytes which spontaneously generate AP’s which initiate the cardiac cycle.
(primary cardiac pacemaker- in SAN in right atrium)
How do action potentials spread?
-Depolarisation wave
-AP spreads via gap junctions
Causing a coordinated contraction of atria and ventricles
EXCITATION-CONTRACTION COUPLING
How is propagation of an action potential generated?
Ions move into the cell, allowing it to reach TV, this then causes more positive ion channels to open which are shared with the cell next door which then helps to generate the TV there.
How does electrical activity spread throughout the heart?
- initiated at SAN (top of RA)
- causing depolarisation of right/left atria
- hits AVN located in interatrial septum near tricupsid valve
- THE AP SLOWS DOWN WHEN IT HITS THE AVN
- AVN to Bundle of His through annulus fibrosis
- Bundle of His then enters the interventricular septum where it divides into the left/right bundle branches
- these branches then terminate in extensive network of fibres called purkinje fibres
What is the annulus fibrosis & its function?
4 Fibrous rings that separates the atria from the ventricles
- anchors myocardium & cardiac valves
- electrical insulator between the atria and ventricles
Role of the purkinje fibres?
Conduct depolarising wave to ventricles
What do the left/right bundle branches do?
Right: travels along right side of the inter-ventricular septum to excite the right ventricle
Left: travels along left side of the inter-ventricular septum to excite the left ventricle
What is the function of the SAN?
- sets HR and sinus rhythm
- fastest rate of depolaristaion in heart
- 60-100 times per min
What is the function of AVN?
- slows conduction
- giving time for stria to contract before ventricles
- firing rate 40-60 times per min without stimulation from the SAN
Can the ventricles cause AP firing?
Yes, they have an electrical conducting system but it is not usually manifested
-firing rate 20-40 times per min
What does an ECG measure?
Changes in electrical potential mVolts produced in successive areas of the myocardium
What does an ECG lead mean?
- cable
- electrical view of the heart obtained from the electrodes
- records electrical activity transmitted to chest wall/limb
How many electrodes are used to record an ECG & how many leads are there?
10 electrodes (6 on chest, 4 on limbs)
(connected by 10 cables to the machine)
-12 leads
What is the function of the right leg electrode?
Grounding electrode (not used for any leads)
Where are the limb leads attached and how many are there?
3 limb leads which are BIPOLAR 1: voltage difference between RA and LA (LA is positive electrode) 2: voltage difference between RA and LL (LL is positive electrode) 3: voltage difference between LA and LL (LL being the positive electrode)
What is a bipolar lead?
They have negative and positive electrodes
Which direction do leads go?
Positive to negative to look at
but the current goes from negative to positive
What are the augmented limb leads?
aVR
aVL
aVF
These are all unipolar- only have a positive electrode
The other electrode is the average of the 2 remaining ones, acting as neutral/reference
What is the aVR?
Positive electrode on the right arm
other two electrodes on the LA and LL
What is the aVL?
Positive electrode on the left arm
other two electrode on the RA and LL