lecture 12 Flashcards

1
Q

cancer proprities

A
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2
Q

properities of cancer cell

A
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3
Q

cancer cell loss

A

contact inhibition and have altered morphology

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4
Q

cancer caused by

A

accumulation mutation that activated oncogenes and inhibit tumor suppressores

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5
Q

single transduction pathway

A
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6
Q

scr functions downstream of integrins factor recptor

A
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7
Q

ras

A

bladder carcinoma

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8
Q

met oncogene

A

hepatocarcinoma

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9
Q

hst

A

stomach carcinoma

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10
Q

erb b

A

breast cancer

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11
Q

ras GTPNGDP CYCLE

A
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12
Q

RAS DO

A
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13
Q

HOW ARE PROTO ONCOGENE CONVERTED TOONCOGENES

A
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14
Q

C MYC IS OFTEN OVER EXPRESSED DUE TO

A

CHROMOSOMAL TRANSLOCATION

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15
Q

C MYC IS TRANSCRIPTION FACTOR

A
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16
Q

CELL cycle progression is controlled by

A
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17
Q

control of G1 to s phase movement

A
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18
Q

the restriction point is controlled by phosphorylation of pRb

A
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19
Q

p53 is tumor supporessor

20
Q

p53 is actived when

21
Q

the oncogenic checkpoint

22
Q

the hallmarks of cnacer

23
Q

sustaining proliferative signaling

24
Q

dna turmor viruses target pRB and p53

25
Q

evading growth suppressor

26
Q

resisting cell death

27
Q

caspase targets

28
Q

two major apoptotic pathways

29
Q

resisting cell death

30
Q

the death recptor pathway

31
Q

the basic Extrinsic apoptotoic pathway

32
Q

the mitochondrial intrinsic pahtway

33
Q

apoptosis controlled by the balance of

A

proapoptotic and prosurvivial factors at the mitochondria

34
Q

the mitochondrial apoptotic pathway

36
Q

inducing angiogensisi

37
Q

angiogensisi is controlled by

38
Q

limitless preplicative potential

39
Q

telomer lenght vs cell divisons

40
Q

telmomeres is

41
Q

telomerase and dna replication

42
Q

enter telomerase

43
Q

transcriptional control of metastasis in cancer

44
Q

altered metabliism

45
Q

aktoncogene

46
Q

lifesthle choices decrease cancer