Lecture 11: Scrotal and Penile Disorders Flashcards
What is a hydrocele?
Accumulation of fluid around the testis.
What is the MCC PAINLESS scrotal swelling in pediatrics?
Hydrocele
What are the 3 noncommunicating hydroceles?
- Testicular
- Inguinoscrotal
- Cord
What connection makes a hydrocele communicating?
Processus vaginalis
Usually only present in newborns.
What are the usual S/S of a hydrocele?
- Little to no pain
- Fluid-filled mass ANTERIOR to testis
- +/- scrotal fullness or heaviness
What does a hydrocele look like on PE?
Like a little lightbulb on your penis
Transilluminates
What imaging should we order if we suspect torsion related to a hydrocele?
Doppler US
When do we treat a hydrocele?
If it lasts > 12months, communicating, or symptomatic.
What is the treatment for a hydrocele?
- Needle aspiration
- Definitive tx: Hydrocelectomy
Describe a variocele.
Dilated, engorged, tortuous veins within the pampiniform plexus of scrotal veins.
MC on the LEFT SIDE
What is the most surgically correctable cause of male infertility?
Variocele
What might an unilateral R variocele suggest in terms of underlying etiology?
IVC obstruction.
What are the S/S of a variocele?
- Scrotal enlargement or heaviness
- +/- dull aching pain
- Infertility
- Asymptomatic is possible too.
Can also be painless like a hydrocele.
What does a variocele feel like on PE?
Bag of worms that may improve with supine.
What is the primary imaging test that can confirm dx of a variocele?
Doppler US
What is the conservative approach to variocele treatment? Surgical tx?
- Conservative: Scrotal support and NSAIDs
- Surgical: only for severe s/s or fertility.
What are the surgical tx options for a variocele?
- Embolization of spermatic vein
- Injected ablation of spermatic vein
- Surgical ligation of pampiniform plexus
What is a testicular torsion?
Twist in the spermatic cord causing compromised testicular blood supply.
EMERGENCY!
What age group are testicular torsion MC in?
12-18 yr old
65%
What are the risk factors for testicular torsion?
- Trauma
- Vigorous exercise or sex
- Cryptorchidism
- Bell-clapper deformity
What are the symptoms of testicular torsion?
- Sudden onset of severe, unilateral scrotal pain/swelling
- +/- lower abd pain, N/V
- +/- hx of intermittent symptoms
- NO VOIDING SYMPTOMS
What is the classic presentation of testicular torsion?
- High-riding testis
- Slightly larger than unaffected testis
- Transverse lie in scrotum
What is Prehn’s sign?
Pain does not relieve with scrotal support
Negative Prehn’s sign
Seen in testicular torsion.
Negative prehn’s => torsion
Positive prehn’s => epididymitis
What is the cremasteric reflex?
Stroke/pinching skin or upper thigh should cause ipsilateral rise of testis.
Lack of this reflex suggests torsion.
What is the test of choice for testicular torsion?
Doppler US
What is the alternative to doppler US for testicular torsion?
Radionuclide scintigraphy
What is the purpose of UA in testicular torsion?
R/o infection
How do we treat testicular torsion?
Detorsion and fixation of testes
Either manual or surgical.
How is manual detorsion done?
Medial-to-lateral primarily.
Opening a book motion.
How quickly must surgical detorsion be performed?
6 hrs!
If > 12 hrs, you might lose your balls
What are the 5 criteria for the TWIST scoring system?
- Testicular swelling - 2
- Hard testicle - 2
- Absent cremasteric reflex - 1
- N/V - 1
- High-riding - 1
5+ high risk, 3-4 medium: do doppler US.
What is the most likely testicular appendage to be twisted?
Appendix testes
Also MC in younger patients!
What are the 4 possible testicular appendages that can undergo torsion?
- Appendix testis
- Appendix epididymis
- Paradidymis
- Vas aberrans
How does testicular appendage torsion present?
- Similar to testicular torsion but less severe.
- Blue dot sign
- Normal blood flow
What is the treatment for testicular appendage torsion?
Conservative
What is phimosis and the MCC?
- Contracted foreskin that can’t retract.
- MCC: chronic infection from poor hygiene.
What demographic is pathological phimosis common in?
Diabetic older men with chronic balanoposthitis
What are the S/S of phimosis?
- If infected, edema, erythema, and tenderness of prepuce can be present.
- Ballooning of prepuce during urination
What are the treatment options of phimosis underlying etiologies?
- Fungal: topical clotrimazole or nystatin or oral fluconazole
- Bacterial: Topical bacitracin, oral metronidazole
- Cellulitis/shaft: cephalexin
What are the temporary treatment options for phimosis?
- Hemostat dilation
- Catheterization
- Topical steroids
- Frenar stretch
- Surgical dorsal slits
When might circumcision be recommended for phimosis?
- Recurrent/persistent
- Chronic balanitis or balanosthitis
What are the two dangerous complications of phimosis?
- Preputial calculi
- Squamous cell carcinoma
What is paraphimosis?
Inability to reduce previously retracted foreskin.
Much more severe than phimosis.
What parasite is a cause of paraphimosis?
Plasmodium falciparum (malaria)
What happens if paraphimosis persists?
Necrosis, gangrene, and autoamputation.
What are the S/S of paraphimosis?
- Swollen, erythematous, tender foreskin proximal to the glans.
- Donut sign
- Flaccid penis proximal to foreskin
Its like a penis ring
How do you perform manual reduction of paraphimosis?
- Pressure for 5 mins on glans to reduce edema.
- Push glans proximally while pulling prepuce distally.
What are the 3 options after manual reduction of paraphimosis fails?
- Needle decompression
- Dorsal slit to foreskin
- Osmotic agents
Circumcision after inflammation subsides.
What is priapism?
Prolonged and painful pathologic erection
What is the MC etiology of priapism? 2nd MC?
- # 1: idiopathic
- MC known cause is intracavernous injection ED treatment.
What diseases can cause priapism?
Leukemia, SCD, cancer
In children, SCD is the MCC.
What is high flow priapism?
- Nonischemic, presenting without pain.
- Characterized by loss of penile arterial regulation.
- Treated with embolization for aneurysms.
High flow = arteries
What is low flow priapism?
- Ischemic, more common and painful.
- Characterized by venous drainage
- Results in impotence
veins = slower
What are the S/S of each priapism?
- High flow: painless, prolonged
- Low flow: several hours of painful erection
- Low flow: glans penis and corpus spongiosum are soft and uninvolved.
- Low flow: Corpora cavernosa - tense, congested blood, tender.
- Low flow: urologic emergency.
What are the treatment options for priapism?
- Anesthesia
- SubQ terbutaline
- Corporal aspiration of viscous blood with irrigation
What are the treatment options for refractory priapism?
- Winter procedure: fistula
- Excision of tunica albuginea
- Shunts
Shunt options:
Cavernosa-spongiosum
Saphenous vein-cavernous
What is Peyronie’s disease?
- Fibrosis of dorsal covering sheaths, aka tunica albuginea.
- Makes a curved penis when erect.
- MC in middle-aged men and older.
What are the primary causes of Peyronie’s disease?
- Trauma during sex
- Vasculitis or CT disease
- DM and hypercholesterolemia
- Smoking, ETOH, Dupuytrens
- Genetic predisposition
How does Peyronie’s look like?
- Painful erection and curved penis
- Poor erection distal to the curvature
- No pain if not erect.
looks like someone just bent half of it
What is the initial treatment for Peyronie’s?
Observe it
If we do decide to treat Peyronie’s, what are the options?
- Vit E, colchicine, para-aminobenzoic acid
- Intralesional injections of PTH, verapamil, etc
- Radiation therapy
- Excision of the plaque
- Penile prosthesis
What is the MCC type of penile cancer?
Squamous cell carcinoma
MC in underdeveloped countries.
What age is typical for penile cancer to present?
Around 60 yo
What two viruses are risk factors for penile cancer?
- HPV
- HIV
What are the S/S of penile cancer?
- MC: skin abnormality or palpable lesions
- Inguinal LAN
- Metastatic symptoms
Symptoms:
Bone pain
Cough
Skin lesions
How do we initially treat penile cancer? 2nd?
- ABX if s/s of infection are present.
- Biopsy if no improvement or no s/s of infection.
What are the two surgical treatment options for penile cancer?
- Low risk of recurrence: limited excision
- High risk of recurrence: partial or total penile amputation
Who is STD epididymitis MC in?
- Men < 40, associated with urethritis.
- N. gono
- Chlamydia
Who is non-STD epididymitis MC in?
- Men > 40
- Associated with UTI or prostatitis
- G- rods
What medication is most often implicated in causing epididymitis?
Amiodarone
What are the S/S of epididymitis?
- Post strain
- Fever
- Pain/swelling in scrotum (normal early)
- +/- hydrocele
- +/- inguinal LAN
- Positive Prehn’s (elevating scrotum will help, unlike torsion)
What would we see on an urethral swab for epididymitis if it is an STD?
- Gonorrhea: G- intracellular diplococci
- Chlamydia: WBC without visible organisms.
What lab could we order to help confirm if a STD is causing epididymitis?
PCR
What is the empiric ABX regimen for epididymitis?
- Rocephin + Doxy
10d, gono + chlamydia coverage
What is the ABX regimen for epididymitis if STD is highly UNlikely?
- Levofloxacin
- Bactrim DS
10d, G- rod coverage?
What are the usual causes of orchitis?
- Bacterial: complication of epididymitis
- Granulomatous: autoimmune response to sperm
- Viral: MUMPS, EBV, coxsackie, VZV, echovirus
Orchitis typically co occurs.
What are the S/S of orchitis?
- Swelling, tenderness, and erythema of testis
- Scrotal pain (gradual onset with less pain than torsion)
- Fever, +/- N/V
- +/- inguinal LAN
What is the only difference in treatment for orchitis compared to epididymitis?
If anal sex is occurring, rocephin + levofloxacin is used.
What disease might predispose someone to a epididymal cyst?
Von-hippel lindau syndrome
What is a spermatocele?
A giant epididymal cyst > 2cm.
What cancer is the MC in males 20-35?
Solid testicular tumors
90-95% are germ cell tumors.
What are the risk factors for testicular cancer?
- Cryptorchidism (surgery doesn’t reduce cancer risk)
- Exogenous estrogen during pregnancy
- Infertility
- Whites, but everyone else has increased mortality risk.
What is the MC symptom of testicular tumor?
Painless enlargement of testis.
10% can be asymptomatic.
Where is the MC site of metastases for testicular cancer?
Retroperitoneal abdominal lymph nodes
What labs can be tested as a biomarker for testicular cancer?
- AFP
- hCG
- LDH
Germ cell tumors can secrete hCG
What is the initial imaging modality for testicular cancer?
Scrotal US
Staging is with CT or CXR.
What is the definitive diagnostic modality for testicular tumors?
Radical inguinal orchiectomy.
Cannot simply biopsy.
What are the treatment options for testicular tumors?
- Inguinal exploration + vascular control of spermatic cord.
- Radical inguinal orchiectomy
How often should followup be for testicular cancer?
- Monthly for 1st 2 years!
- CXR/CT
- Tumor markers at every visit
80% relapse in 1st 2 yrs
What is the prognosis for testicular tumors?
90% 5-year survival rates