Lecture 11: Neuron As A Molecular Marker 4 Flashcards
1
Q
What happens when light illuminates channel rhodopsins (ChRs)? What colour light?
A
They depolarise neurons upon illumination. ChR1 responds to red right and ChR2 responds to blue light.
2
Q
What happens when light illuminates halorhodopsins (HRs)? What colour light?
A
Hyperpolarise neurons upon illumination. Responds to yellow light.
3
Q
What are OptoXRs and what do they do?
A
They are rhodopsin-G protein coupled receptor chimeras that activate signalling cascades upon illumination.
