Lecture 10: The Immune System Flashcards

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1
Q

What are factors from immune system protect your body?

A

think of a castle
Physical Barriers (non-immune) Skin, mucous membranes, etc.
The Innate Immune System
Inborn mechanisms
The Adaptive Immune System
Learned or designed in response to something new

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2
Q

What is the immune system and how?

A

The function of your immune system is to keep you alive
Tolerance vs Response
Self or Non-Self
Harmless or Dangerous

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3
Q

What does it mean when improper cells invade the body ?

A

It’s called autoimmune diseases

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4
Q

What are the functions of a antibody?

A

Antibodies attach to antigen forcing them to clump together. Prevents the pathogens to enter the host.

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5
Q

Which response produces more antibodies?

A

Secondary response

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6
Q

Why get vaccinated?

A

You have a secondary response (memory)when you encounter the pathogen.

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7
Q

What is the purpose of B cells when encountering an antigen?

A
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8
Q

What are the differences between primary vs. secondary antibodies?

A

Primary antibodies identical sequences. Secondary antibodies exhibit variation and varies in affinity allowing the high affinity binding can kill effectively.

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9
Q

How do antibodies produced by B cells contribute to an immune response?

A

2 types of response antibodies attach to antigens, to prevent pathogens to enter a host cell.

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10
Q

Which response produces B cells and why?

A

2nd immune response has a high concentration and the memory B cells are produced antibodies due their affinity antigen compared to primary response B cell.

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11
Q

Can vaccine alter your primary response to an antigen ?

A

Allows you make memory B cells that allow you to fight off the infection 2nd time you see the pathogen.

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12
Q

What binds allergens to start an immune response?

A

antibodies

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13
Q

When do you have the highest antibody production ?

A

Secondary response

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14
Q

Which components of the immune system do you expect to have the fastest response to an invading pathogens?

A

Innate immune system

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15
Q

What factors allow the secondary immune response to be larger than primary response?

A

Memory B cells can produces many antibody producing B cells and many of secondary B cells have higher affinity for the antigen than the primary response B cells.

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16
Q

Which types of B cells are most likely to survive?

A

B cells with very high affinity for antigen

17
Q

Do B cells undergo cellular evolution by natural selection?

A

Yes, B cell response show all 5 tenets of natural selection.