LECTURE 10 (Hydrostatics) Flashcards

1
Q

What are the properties of Fluid?

A
  • Cannot maintain equilibrium condition under various influences
  • Deforms/begins movement due to influence
  • Fluid compression is very low
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2
Q

What is Pressure?

A

The force per unit area applied in a direction perpendicular to the surface of an object

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3
Q

What is Liquid pressure?

A

The force per unit area of hard substance from liquid layer or liquid itself

P = F/S

P - Fluid pressure
F - Pressure force
S - Surface area

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4
Q

What is the equation for Pressure force?

A

F = PS

F - Pressure force
P - Fluid pressure
S - Surface area

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5
Q

What is pressure measured in?

A

Pascal (Pa)

Explanation: Pressure equals 1 Pascal, if per 1 m2 area surface is influenced by 1 Newton force

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6
Q

What does Pascal’s law state?

A

Pressure exerted anywhere in a confined incompressible fluid is transmitted equally in all directions throughout the fluid

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7
Q

What is Fluid hydrostatic pressure?

A

The pressure of non-moving (static) fluid determined by exertion of gravity forces on fluid (fluid mass)

Hydrostatics is based on two principles:
- Pascal’s law
- The pressure ratio remains the same in all points of horizontal plane

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8
Q

What is the difference between water horizontally and vertically?

A

Horizontally = water pressure is the same (P1 = P2 = P3)

Vertically = water pressure increased with depth (pgh = density x gravity x height)

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9
Q

What is the U-pipe principle?

A

Pressure increase in one bend of U-pipe causes pressure increase in another bend with the same value

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10
Q

What does Atmospheric pressure equal?

A

The weight of mercury

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11
Q

What is the standard atmosphere?

A

A unit of pressure defined as 101325 Pa or 760 mmHg

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12
Q

What is a Manometer?

A
  • Comprised of a bulb containing a gas and a U-shaped tube partially filled with mercury
  • Measure static pressure
  • If both ends of U-pipe fluid level equal -> object’s pressure is equal to atmospheric pressure
  • If open bend of manometer fluid level raises -> object’s pressure is higher than atmospheric pressure
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13
Q

What is the difference between fluid levels in manometer bends determined by?

A

Δp value
[Δp = h]

Explanation: Δp value shows how object pressure differs from atmospheric pressure

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14
Q

What is Decompression sickness?

A

Also called “the bends”, Caisson sickness or “diver’s disease” is a life threatening condition caused by a buildup of nitrogen bubbles in the bloodstream and body tissues

CAUSE:
As a diver descends, pressure increases -> Nitrogen is absorbed into the body tissues -> Diver must ascend SLOWLY to allow nitrogen to escape out of the body -> If diver ascends too fast, nitrogen becomes bubbles in the tissue + bloodstream

SYMPTOMS:
- Unusual fatigue
- Skin itch
- Pain in joints and/or muscles of arms, legs or torso
- Dizziness, vertigo, ringing in ears
- Numbness, tingling and paralysis
- Shortness of breath

TREATMENT:
Recompression in a HIGH-PRESSURE HYPERBARIC CHAMBER in which the patient is put back under pressure and receives 100% oxygen -> reverses pressure changes that allows gas bubbles to form + drives back into liquid form that can be gradually cleared

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15
Q

Pressure in a mixture of gases follows which principles?

A
  • Each gas exerts the same pressure that it would if it alone occupied the container
  • Pressure each gas exerts is called its “Partial pressure” and the total pressure is “the sum of the partial pressure of the constituent gases”
  • Ratio of the partial pressure of any component to the total pressure equals the ratio of its partial volume to the total volume
  • Gasses dissolved in water also exert pressure (since move randomly + have kinetic energy)
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16
Q

What is the Ideal gas equation?

A

PV = nRT

P - pressure
V - volume
n - number of moles
R - universal gas constant
T - absolute temperature

17
Q

What is Dalton’s law of partial pressures?

A

The total pressure of a mixture of gases is equal to the sum of the partial pressures of the component gases

18
Q

What does a pressure of 50mmHg in a blood vessel mean?

A

It means that force of blood is sufficient to push a column of mercury up level 50mm

19
Q

What are the difference reference points for measuring blood pressure?

A
  • Atmospheric pressure is used as zero reference point (90mmHg means 90mmHg above atmospheric pressure)
  • Position of heart (patient positioning must be at cardiac level)
20
Q

What is Blood pressure?

A

The pressure exerted by the blood at right angles to the walls of blood vessels (Pi) minus the environmental or ambient pressure (Pa)

BP = Pi - Pa

21
Q

Which equation allows us to convert BP in mmHg into pascals?

A

P= ρHggh/1000 (Pa)

ρHg - specific density of Hg
g - gravitational acceleration
h - value of BP in mmHg

22
Q

What are the factors that influence blood pressure?

A
  • Cardiac constriction power (increase cardiac constriction power -> increase BP)
  • Blood volume (increase cardiac output -> increase BP)
  • Resistance (increase resistance -> increase BP)
  • Blood viscosity (increase viscosity -> increase resistance -> increase BP)
23
Q

What factors increase resistance in blood vessels?

A
  • Vessel size (larger vessel -> decrease resistance)
  • Vessel wall smoothness (fatty plaques form -> resistance increased -> flow becomes turbulent)
  • Vasoactive compounds (alters vessel diameter)
24
Q

What are the properties of BP?

A
  • Varies during the day (Circadian rhythm)
  • Changed in response to stress, nutrition factors, drug influence and during various diseases
25
Q

Describe the pathways of blood pressure in the vessel network

A

Blood pressure is high when leaving via aorta (around 100mmHg) -> As heart performs pulse work, arterial pressure is changed between systolic (120mmHg) and diastolic (80mmHg) pressures -> Progressively decreases and at penetrating into right ventricle is zero

26
Q

What is Stroke volume?

A

Volume of blood in mm ejected from each ventricle due to the contraction of the heart muscle which compresses these ventricles

SV = EDV - ESV

EDV - End diastolic volume
ESV - End systolic volume

measured in ml/m2

27
Q

What is cardiac output?

A

Amount of blood the heart pumps from each ventricle per minute

CO = HR X SV (heart rate x stroke volume)

28
Q

What are the factors affecting heart rate?

A
  • Autonomic innervation
  • Hormones
  • Fitness levels
  • Age
29
Q

What are the factors affecting stroke volume?

A
  • Heart size
  • Fitness levels
  • Gender
  • Contractility
  • Duration of contraction
  • Preload (EDV)
  • Afterload (resistance)
30
Q

What is Venous pressure?

A

Blood pressure in a vein or in the arteries of the heart. It’s less than arterial BP, with 5mmHg in the right atrium and 8 mmHg in the left atrium

31
Q

What is Central venous pressure?

A

The pressure of blood in the thoracic vena cava near the right atrium to provide information about the body volume status and right ventricular function

Normal CVP = 0-8 mmHg
Less than 0 = Hypovolemia
More than 0 = Hypervolemia

32
Q

What are the properties of Central venous pressure?

A
  • Reflects the amount of blood returning to the heart and the ability of the heart to pump the blood into the arterial system
  • Good approximation of right atrial pressure -> major determinant of right ventricular end diastolic volume
33
Q

What does gravity in the upright human body cause?

A

A vertical gradient of venous pressures

34
Q

How does lying supine increase pulse pressure?

A

Increased central venous pressure -> increased end-diastolic volume -> increased stroke volume -> increased pulse pressure -> blood evenly distributed in veins

35
Q

What is Mean arterial pressure?

A

The average arterial pressure during a single cardiac cycle

MAP = (stroke volume x systemic resistance) + CVP

MAP = Diastolic + 1/3 pulse pressure

36
Q

What is Pulse pressure?

A

Systolic minus diastolic blood pressure

Pulse pressure = systolic - diastolic

Low values: error of measurement or if really low -> congestive heart failure and or shock

High values: stiffness of major arteries, aortic regurgitation, hyperthyroidism -> can accelerate the normal ageing of body organs

37
Q

What is Orthostatic hypotension?

A

Gravity reduces the rate of blood return from the body veins below the heart back to the heart, reducing stroke volume and cardiac output

[a few seconds are needed for recovery otherwise pt will suffer reduced blood flow to brain resulting in dizziness + potential blackout]

38
Q
A