Lecture 1: Renal Anatomy and Histology Flashcards
What is a bifed ureter?
A ureter that comes out as two and then fuses together eventually.
Label A-D
A) Proximal Convoluted Tubule
B) Distal Convoluted Tubule
C) Mitochondria
D) Brush Border
_________nerve fibers from the _______ plexus stimulate the secretion of _________
Sympathetic nerve fibers from the renal plexus stimulate the secretion of renin
Functions of Interstitial Cells
- Maintenance of Renal Architecture
- Produces Erythropoietin (EPO)
Label the top and bottom arrow
Top arrow: Mesangial Cell
Bottom arrow: Mesangial Matrix
What is this structure?
Proximal Convoluted Tubule
Components of capsule of bowman?
- Double layered
- Parietal and visceral components
- Podocytes
Label from top arrow to bottom
Top: Mesangium
Podocyte
Glomerular capillary
Bottom: Parietal Layer
What 2 cells make up the collecting tubule; distinguishing features?
1) Principle Cells - Stain light - Mechanosensor
2) Intercalated Cell - Stain Dark - Lots of Mitochondria
Label A-D
Parasympathetic control of kidneys (functions)?
- Vasodilation
- Inhibits Urinary Sphincter
What structures are found in the renal medulla?
Medullary pyramids, Renal Papilla, and Renal Columns
Sympathetic control of kidney (functions)?
- Vasoconstriction
- Slow urine formation
- Contract urinary sphincter
If we are in a capillary to get to the urinary space, what’s the path?
Go between fenestrations of the capillary (endothelium), past the basement membrane, through the filtration slits between the pedicles of the podocytes
endothelium –> basement membrane –> between pedicles of the podocytes
Differentitate histologically the difference between the thick and thin segments of the loop of henle
Thick - Low simple cuboidal epithelium
Thin - Simple squamous epithelium (1 layer thick)
What are the 3 uteric constriction points?
1) Junction of Ureter and Renal Pelvis
2) Pelvic Brim
3) Urinary Bladder
*Places where kidney stones are most likely to get stuck
What are the 3 blood supply branches coming off the abdominal aorta; which ones are the Renal As.?
1) Unpaired Visceral Branches
2) Paired Lateral Visceral Branches (Renal As.)
3) Paired Segmental Parietal Branches
Label A and B
A) Capillary Loops
B) Bowman Capsule
What is the single biggest difference in the proximal vs the distal convoluted tubule?
Proximal has microvili on the surface, “brush border”
*More basal mitochondria in proximal
What do we call the fat that goes inside the kidney?
Perirenal fat
Which kidney is more superior?
Left is more superior, right sits more inferior due to liver.
What structures are found in the renal sinus?
Minor Calix, Major Calix, and Renal Pelvis