Lecture 1- Heredity and DNA

Question 1

What is the progeny of offspring replication similar to?

Answer 1

their parents

Question 2

What does transmission genetics involve?

Answer 2

-the examination of the
patterns of inheritance

Question 3

What are experiments designed for?

Answer 3

so that the transmission of traits can be analysed through several generations

Question 4

Define allelic segregation

Answer 4

the segregation of 2 alleles during meiosis.

Question 5

Define cytogenetics

Answer 5

the application of cytology (study of cells) and cytological techniques to the study of inheritance

Question 6

Summarise Griffiths transformation process

Answer 6

A “transforming principle” from the virulent strain transforms the avirulent strain to virulence.

Question 7

Describe Dawson’s Transformation experiment

Answer 7

He demonstrated that heat-killed virulent, smooth cells could transform living avirulent rough cells to smoothness in vitro (in test tube)

Question 8

What is the “transforming principle”?

Answer 8

DNA

Question 9

What are some bacteria “naturally competent” to be able to do?

Answer 9

-able to take up naked “pure” DNA

Question 11

How can E.coli be made competent?

Answer 11

by incubating it in Calcium Chloride solution