Lecture 1- Brainstem I Flashcards
Basic internal components of brainstem
Ascending/descending pathways Cranial nerve nuclei Neuromodulatory nuclei Intrinsic nuclei Reticular nuclei
Cranial nerve nuclei and functions
GSE= Motor (gen somatic efferent) GVE= Parasympathetic (gen visceral eff) GSA= General sensory SVA= Special sensory
Neuromodulatory nuclei
Raphe nuclei (serotinergic) Substantia nigra (dopaminergic) Locus coeruleus (noradrenergic) Area postrema (adrenergic), lateral dorsal tegmental and pedunculopontine (cholinergic)
Function of neuromodulatory nuclei
Modulate neuronal activity over larger parts of the entire brain
Intrinsic nuclei
Form connections and undertake functions within regions of brainstem
Inferior olive
Region where impulses from cerebellum, SC, cerebral cortex and channels into the cerebellum are correlated for coordination of learned movement patterns
Reticular formation
Continuous core, traverses entire brainstem
Continuous below with reticular intermediate spinal grey laminae
Reticular formation divisions
3 longitudinal columns
- median
- paramedian (mostly large reticular neurons)
- lateral (small to intermediate neurons)
Characteristics of reticular formation
Ill-defined collections of neurons and fibres with diffuse connections
Conduction pathways are difficult to define, complex and polysynaptic
Have ascending and descending components, partly crossed and uncrossed
Components are associated with somatic and visceral function
Functions of reticular formation
Coordination of muscle movement modulate pain sensation eye movements conscious state speed of reflexes Regulation of feeding, respiration and circulation Drug induced vomiting Habituation
Midbrain external features
Swellings
Peduncles
Cranial nerve
Nuclei
Midbrain components
Tectum/colliculi
Tegmentum
Substantia nigra
Basis pedunculi
Midbrain fibre pathways
Corticobulbar and corticospinal tracts
Midbrain cranial nerve nuclei
Oculomotor (III) and trochlear (IV)
Midbrain neuromodulatory nuclei
Dorsal raphe (serotonergic) Substantia nigra (dopaminergic) Ventral tegmental area (dopaminergic)