Lecture 1 Flashcards
All eukaryotes that have been studied have at least ______ chromosomes
two
DNA molecules are always (circular/linear)
linear
In order for the genome to fit into the nucleus it must be ______
packaged
Define genome
the complete haploid genetic complement of a cell
define transcriptome
the genes expressed in a cell under a given set of conditions
define proteome
The complement of proteins present in a cell under a given set of conditions
what is a haploid cell?
one copy of a gene
What do nucleosomes consist of
Core histones + linker histones + ~180bp dsDNA
what are the core histones?
2H2A, 2H2B, 2H3 and 2H4
what are the linker histones?
H1a-e, H1o, H1t, and H5
A single (core/linker) histone is attached to each nucleosome.
linker
Chromosomes are characterized by having a _______ which has a specific position within each chromosome.
centromere
Define telomeres
The terminal ends of the chromosomes
Define chromatids
the arms of the chromosome
when do chromatids become easily visible?
after chromatin condensation