lecture 1

Question 1

Testing

Answer 1

IRB
Animals
Cell culture - earliest trial
(premolars extraction was planned 1950-1970)
(test on duration, stress, and function)

Question 2

inflammation can be caused by

Answer 2

toxicity
mutagenicity
allergy

Question 3

allergic reactions and dosage

Answer 3

DOSE INDEPENDENT

Question 4

inflammation and dosage

Answer 4

DOSE DEPENDENT

Question 5

edema vs erythema

Answer 5

edema - fluid coming out in cavity

erythema - superficial redness

Question 6

acute vs chronic

Answer 6

acute - sudden quick

chronic - slow persistent

Question 7

mutagenic

Answer 7

substance alters DNA bp

irrelvant to mutation

Question 8

NO dental material is carcinogenic

Answer 8

a

Question 9

local vs systemic

Answer 9

local - pulp, periodontal, apical, tongue, buccal, labial mucosa
systemic - ingested, inhaled, released at apex, absorption through mucosa, blood/lymph

Question 10

Enamel is permeable or not?

Answer 10

Permeable tissue
How teeth is bleached - change in color of dentin
(travel thru enamel and reach dentin then oxidize then change color)

Question 11

precious with nonprecious

Answer 11

precious + nonprecious creates electrick shock -> create galvin reductive reaction -> degrade material

Question 12

things that can happen to material

Answer 12

corrosion/degradation
oxidation (rust)
electrochemical
mechanical
body's response to digestion
acidic/alkalic environment

Question 13

immunotoxicty

Answer 13

lichenoid reaction

plasma cell gingivitis

Question 14

odonteoblast

Answer 14

start blasting dentin cells -> start from pulp all the way to emanto junction

Question 15

Periodontal interface

Answer 15

Pocket
JE
PDL - periodontal ligament
cementum

Question 16

Periapical

Answer 16

apex of tooth root

Question 17

Dentin-resin interface

Answer 17

chemical and mechnical

leakage

Question 18

implant-bone interface

Answer 18

osseointegration
biointegration
(no idea make sure to understand)

Question 19

MSDS (SDS)

Answer 19

tells you what can happen, potential adverse affect

Question 20

Berylium

Answer 20

in alloy

Question 21

Methacrylate

Answer 21

white filling material

Question 22

esttrogenicity

Answer 22

mutational change in DNA