Lecture 1

Question 1

Barometric Pressure

Answer 1

700mmHg

Question 2

pO2

Answer 2

% x ATM

~140mmHg

Question 3

Importance of O2?

Answer 3

produce ATP

Question 4

Hct

Answer 4

homatocratin - percentage of RBC

= 45%

Question 5

[Hb}

Answer 5

males - 13-17.5 g/100ml blood

females - 12-15.5

Question 6

different types of hemoglobin?

Answer 6

alpha-beta = 95%
alpha-delta = 2-3%
(fetal)
alpha-gamma= 2-3%

Question 7

factors affecting hemoglobin type concentrations

Answer 7

age
diet (SCFA inc. fetal)
anemia
drugs (affect 2nd unit)
hydroxy urea (expansion of gamma - fetal)

Question 8

Blood oxygen content formula

Answer 8

CaO2 = oxygen bound to Hb + dissolved oxygen

(ideal) 1.39 x [Hb] 15g/dL x (saturation) 0.98 + 0.003 x (PO2) 100

Question 9

VO2 rest

Answer 9

250-300ml(kg x time?)

Question 10

PaO2 and PvO2

Answer 10

100mmHg

40mmHg

Question 11

PaCO2 and PvCO2

Answer 11

46mmHg

50mmHg

Question 12

Henrys constant

Answer 12

pressure proportional to saturation

ex. elevation
pressure decrease = saturation decrease

Question 13

p50

Answer 13

lower the p50
higher the affinity
less released to muscles

and vice versa

Question 14

how to increase RBC

Answer 14

altitude (live high train low)

EPO (doping)

Question 15

How to release more O2 to body?

Answer 15

increase:
pO2
temp 
CO2- haldane effect
BPG - inorganic ions (takes days)

decrease:
pH (increase [H+]) - Bohr Effect

Question 16

Co2 in blood

Answer 16

Bicarbonate (70%)
- HCO3-

Carbamino (23%)
- on Hb

Disolved (7%)
- 20x more than o2

Question 17

Flow (Q)

Answer 17

5L/min

Question 18

VO2 rest

Answer 18

250-300 ml of o2 / (kg*min)