lecture 1/2 Flashcards

1
Q

Genes come in multiple
forms called…

A

alleles

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2
Q

Genes are located on…

A

chromosomes

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3
Q

Genetic information is…

A

transferred from DNA to RNA to protein

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4
Q

meiosis 1

A

segregate the homologous chromosomes

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5
Q

meiosis 2

A

separate the sister chromatids

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6
Q

Null/Amorphic Alleles

A

A nonfunctional protein is produced OR no protein is produced

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7
Q

Hypomorphic Alleles

A

A poorly functioning protein is produced OR reduced amounts of a normally functioning
protein is produced 39

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8
Q

multiplication rule

A

and

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9
Q

addition rule

A

or

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10
Q

Dominant Mutations Often Involve…

A

Gain/Change of Gene Function

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11
Q

Recessive Mutations Often involve…

A

loss of gene function

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12
Q

Dominant Hypermorphic Alleles

A
  • Negative phenotypic consequences due to the over- production of a normal protein OR
  • Negative phenotypic consequences due to the production of a protein with increased activity levels
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13
Q

Neomorphic Alleles

A
  • Negative phenotypic consequences due to the presence of an altered protein that has a new function
  • Negative phenotypic consequences when the altered protein interferes with the wildtype protein (Dominant-negative allele)
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14
Q

For traits that are rare and dominant, affected
individuals are most likely to be…

A

heterozygous

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15
Q
A
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