Lecture 1 Flashcards
unicellular example
bacteria
multicellular
plants and animals
multi or unicellular
protists and fungi
4 things cell division is important for
- reproduction
- growth
- wound healing
- replacing dead cells
What 3 things does cell division require
- replication of genetic material
- accurate segregation of genetic material
- division of cytoplasm (liquid in cells) between 2 cells
Prokaryotes
Small cell size
No nucleus
No membrane-bound organelles
DNA in circular chromosomes
Cell division by binary fission
Eukaryotes
Large cell size
Nucleus present
Has membrane-bound organelles
DNA in linear chromosomes (except for mitochondrial and chloroplast DNA)
Cell division by mitosis/meiosis
Binary fission
- cell size increases
- circular bacterial chromosome is replicated
- Replication begins at the origin of replication and proceeds in both directions to the site of termination
- The 2 chromosomes are separated and segregated to opposite ends of the cell
nucleoid
a non-membrane bound region of compacted DNA (contains proteins)
How many base pairs in a single circular chromosome in prokaryotes
4 mil bp
how much do chromosomes need to be condensed
1000x
1st and 2nd level of DNA compaction (prokaryotes)
DNA is looped around SMC proteins to form loop domains
DNA loops are further compacted into supercoils
Septation
- dividing the cell into 2
FtSZ proteins
form a ring around the middle of the cell called a Z-ring
Z-ring
shrinks and continues until the cell is divided into 2 daughter cells