Lecture 1 Flashcards
Bacon
Observations power accurate conclusions
Leeuwenhoek
Developed single lensed microscope with hooke
Hooke
Single lensed microscope with leeuwenhoek
Jenner
Cowpox vaccination against smallpox
Nightingale
Hygiene to avoid infection
Pasteur
Determined microbes as causative agents of disease with Koch
Koch
Determined microbes to be causative agents of disease with Pasteur
Gram
Gram Stain
Erlich
“606” salvarsan or arsphenamine
Fleming
Discovery of penicillin
Chain
Purification and production of penicillin with Florey
Florey
Purification and production of penicillin with Chain
Domagk
Discovered sulfonamides
Avery
Discovered DNA as a transforming principle with MacLeod, McCarty
MacLeod
Discovered DNA as a transforming principle with Avery, McCarty
McCarty
Discovered DNA as a transforming principle with Avery, MacLeod
Sanger
Protein and DNA sequencing
Watson
Discovery of DNA Structure with Circle, Rosalind, Franklin
Crick
Discovery of DNA Structure with Watson, Rosalind, and Franklin
Rosalind
Discovery of DNA Structure with Watson, Crick, and Franklin
Franklin
Discovery of DNA Structure with Watson, Crick, and Rosalind
Roberts
Restriction Enzymes
Boyer
Construction of recombinant DNA with Cohen
Cohen
Construction of recombinant DNA with Boyer
Mullis
PCR
Nucleus
P-
E+
extra chromosomal DNA
P+ (Plasmids)
E+ (Organelles)
Cytoplasmic Organelles
P-
E+
Ribosomes
P+ (70S)
E+ (80S)
Cytoplasmic Membrane
P+ (for respiration, Secretion, DNA synthesis, phospholipid synthesis)
E+ (a semi-permeable layer, no specialized fixation)
Cell Wall
P+ (Peptidoglycan)
E- (sometimes cellulose is present as a “wall”)
Sterols
P-
E+