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becky: research > LECTURE 1 > Flashcards

LECTURE 1 Flashcards

1
Q

what is a CAT?

A

*NON PEER REVIEWED research study

-common way to organize results from clinical EBP question
-dated, only good for short term
-subject to error/bias since made by individual/small group

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2
Q

Pubmed

A

database that gives free access to MEDLINE

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3
Q

CINAHL

A
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4
Q

Cochrane is what

A

database for SYSTEMATIC REVIEWS

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5
Q

PEDro

A

RCTs and systematic reviews
for physical therapy!

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6
Q

any time study or intervention is planned, controlled, not “standard of care,” it is considered….

A

research!
*any study that differs in any way from usual med practice

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7
Q

can you go back and use old medical records and publish data without IRB?

A

NO, even if its just standard of care

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8
Q

What are ways to ethically have a control group?

A

-same intervention with populations of different diagnoses
-two acceptable treatments (exercise vs specialized exercsie)
-1 x/week vs 3x/week

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9
Q

Who uses IRB?

A

every research university
hospitals and clinical companies

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10
Q

what is dual review?

A

when you need approval from 2 IRB committees (if you are conducting study with 2 different institutions/hospitals)

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11
Q

At TWU, our IRB applications are completed using the online system called

A

CAYUSE

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12
Q

When do you use full IRB review?

A

-more than minimal risk
-sensitive topic (race, gender, marginalized populations)
-minors, vulnerable pops

ENTIRE BOARD WILL REVIEW

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13
Q

When do studies get expedited review?

A

-minimal risk (blood draw, physical exam, psych testing)
-observational studies
-questionaires of non-sensitive nature
-EEG
-genomic studies
-non-invasive imaging of basic brain function
-meta-analyses

SUB-SET OF THE BOARD WILL REVIEW

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14
Q

When do you use exempt IRB review?

A

-little risk
-educational settings of normal curriculum
-archival data (anonymous)

CHAIR WILL REVIEW

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15
Q

If your name was not included in the IRB, can you still be considered an author on poster/manuscript?

A

YES

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16
Q

After IRB is closed, can you still analyze data and write manuscript?

A

YES

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17
Q

order of IRB levels from lowest to highest patient risk

A
  1. lowest-EXEMPT
  2. expedited
  3. High: FULL
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18
Q

You are collecting 1-2.5 ml of blood to study A1C levels in healthy adults. what is IRB review?

A

expedited (blood up to 5 mL)

19
Q

You are studying the effectiveness of a new teaching strategy in the School of PT at TWU. You will compare pre and post exam scores that are based on the course content.
What is the correct level of IRB review?

A

school-EXEMPT

20
Q

You are studying glenohumeral labrum thickness in adults using an FDA approved diagnostic ultrasound unit. IRB?

A

expedited

21
Q

You are asking children to share with you their experiences following bone marrow replacement.
IRB?

A

full (children)

22
Q

You are testing a new hand-held dynamometer to assess isometric quadriceps strength in post-op ACL patients.
IRB?

A

FULL (new item, post op)

23
Q

You plan to anonymously watch and record parents leave an elementary school and determine who drives, rides bikes, or walks home.
IRB?

A

exempt

24
Q

integration of:
1. best research evidence
2. clinical expertise
3. patient values/ circumstances
….this is the definition of

A

evidence based practice

25
Q

PICO is used when?

A

developing research question (EBP)

26
Q

what is PICO stand for?

A

patient/problem
intervention (IV)
comparison intervention (control)
outcomes

27
Q

FINER is used when? What does it stand for?

A

Feasible
Interesting
Novel
Ethical
Relevant

*used when planning research study

28
Q

What is Medline? What is PUBMed?

A

Medline is National Library of Medicine’s database. (records are indexed with MeSH)

Pubmed is the free access to MEDLINE

29
Q

books, meta-analyses, reviews, and systematic reviews are all

A

secondary sources

30
Q

what are primary sources?

A

clinical trials and RCTs

31
Q

which databases have primary sources?

A

PubMed/medline, CINAHL, ERIC, PEDro, APTA, OVID

32
Q

which databases are secondary sources?

A

medline/pubmed, cochrane (systematic reviews!) DARE, TRIP, PEDro

33
Q

What is the hierartchy of CEBM levels?

A

1a: stronger evidence
1b
1c
2a
2b
2c
3a
3b
4
5: weak

*individual study

34
Q

what is hierarchy of CEBM grades

A

*summarizes multiple studies

A: STRONG
F: weak

35
Q

1a

A

systematic review/met-analyses of RCTs

36
Q

1b

A

RCT with narrow CI

37
Q

1c

A

ALL OR NONE

38
Q

2a

A

systematic review of cohort

39
Q

2b

A

cohort study or low quality RCT

40
Q

2C

A

outcomes research

41
Q

3a

A

systematic review of case control studies

42
Q

3b

A

individual case control study

43
Q

4

A

case report or small case series

44
Q

5

A

expert opinion without any critical appraisal, bench research

becky: research (8 decks)

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