Lecture 1

Question 1

Molecular Genetics

Answer 1

How gene sequence works

Question 2

Transmission Genetics

Answer 2

Parent to offspring (inheritance)

Question 3

Population Genetics

Answer 3

Allele distribution in a group of individuals

Question 4

Forward genetics

Answer 4

Find a mutant in the wild, map gene, ID what gene does

Question 5

Reverse genetics

Answer 5

Take any wildlife gene, create mutation, assess phenotypic changes

Question 6

Model organisms include;

Answer 6

E.Coli, yeast, fruit flies, C.elegans, Zebrafish, Mice

Question 7

What is the Central Dogma in Biology?

Answer 7

Nucleic acids contain sequence information which codes for functional products.

Question 8

What does ΔF508 stand for?

Answer 8

Δ-deletion, F-phenylalanine, 508- 508th AA

Question 9

What is a gene?

Answer 9

An organization of sequences which fall into two categories; Regulatory and Coding.

Question 10

What is a protein?

Answer 10

Functional product of a gene

Question 11

What is the nature of a gene?

Answer 11

Sequence info with specific components

Question 12

What is the nature of a trait?

Answer 12

Carried out by a protein

Question 13

How does DNA store info?

Answer 13

In the form of base pairs as a double helix

Question 14

What is a chromosome?

Answer 14

A very long double helix. Bigger gene = more codons

Question 15

Define locus

Answer 15

Each gene has a specific position on a chromosome

Question 16

What is a polygenic trait?

Answer 16

A trait that relies on the input of multiple genes

Question 17

What can studying a population show?

Answer 17

Changes in alleles

Question 18

What features make an organism a great model?

Answer 18

Quick generation time, housing costs are low, food/media, space

Question 19

What is Transgenics?

Answer 19

Inserting foreign DNA into host species.

Question 20

What does PCR do?

Answer 20

Exploit the natural process of DNA replication

Question 21

What is an allele?

Answer 21

One of two or more alternative forms of a gene that arise by mutation and are found at the same place on a chromosome.