lecture 1 Flashcards

1
Q

antibody formation: what does IgM and IgG show?

A

IgM: recent infection
IgG: Latent infection: higher in secondary response

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2
Q

Innate Immunity

A

Response is fast and non specific. No memory. Has neutrophils, macrophages, dendritic cells, NK cells and complement

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3
Q

Adaptive Immunity

A

Response is slow on first exposure, momory response is fast. Has T cells, B cells abd circulating antibodies.

can lead to autoimmunity. provides high affinity receptors for antigens

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4
Q

Thymus

A

produces T Cells: life long adaptive immunity

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5
Q

Bone marrow

A

produces B cells

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6
Q

Immunization Natural passive

A

maternal ( moms milk) short term

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7
Q

immunization Natural active

A

infection creates memory that last life long

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8
Q

immunization Artificial Passive

A

antibody transfer

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9
Q

Immunization Artifical Active

A

immunization ( flu shot)

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10
Q

DAMP

A

danger signal, damage signal

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11
Q

PAMP

A

absolutely required for pathogen survival. ex endotoxin

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12
Q

Toll-like receptor

A

innate immune system, reconizes microbes, activates immune response. PAMPS. join together with interlukins. SENSORS FOR PATHOGENS

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13
Q

macrophages, monocytes, and dendritic cells make what?

A

interleukins

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14
Q

Immune cells can produce signalling factors called cytokines, which trigger ____?.

A

inflammation

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15
Q

inflammation induced by endotoxin is an example of

A

PAMP

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16
Q

granular cells

A

leukocytes(neutrophils) (/basophils)

17
Q

non-granular

A

monocytes and lymphocytes( B and T cells)

18
Q

leukocytes

A

identifies non-self using receptors for PAMPs

19
Q

cell found only in circulation

A

monocyte. neutrophil/cytokines if infection

20
Q

what cells express MHC class II

A

dendritic, macrophages and B cells. All cells express MHC I except RBC