Lecture 1 Flashcards
Cardiac Output Equation
CO (L/min) = heart rate (beats/min) x stroke volume (ml/beat
Ion channels
Voltage-dependent membrane-imbedded proteins that pass a particular ion, usually selectively, in one direction (dependent on the electrical and chemical gradients).
Pumps
ATP-dependent and voltage-independent membrane-imbedded proteins that pass usually two different species of ions, uni- or bi- directionally ( affected by chemical and electrical gradients)
Exchangers
Voltage-independent and ATP-independent membrane-imbedded proteins that pass usually two different species of ions, uni- or bi- directionally ( affected by chemical and electrical gradients)
Types of ion channels
Ca2+ channels (L-type and T-type)
- (long- type and transient- type)
K+ channels
Na+ channels
Reprimed Ion Channels
closed but ready to be opened
Activated Ion Channels
Open to allow the flow of ions through them
Inactivated Ion Channels
Closed and cannot be opened