Lecture 07_Spring Flashcards
Garlic is commonly used to lower blood pressure and lipids. Does it need to be stopped before surgery? If so, how far in advance and why?
Yes b/c it is an anti-platelet drug and will cause increased bleeding. It must be stopped 1-2 weeks before surgery
Grapefruit juice has which of the following effects on the serum concentration of intraop drugs?
a) it induces CYP enzymes and increases drug metabolism
b) it inhibits CYP enzyme and decreases drug metabolism
c) it has no effect on CYP enzymes
b
Indications for use of which drug include: jet lag and insomnia?
a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin
e
Indications for use of which drug include: stroke,MI, and artherosclerosis?
a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin
c
True or False. Garlic acts as anti-platelet?
TRUE
What are the cardiac side effects associated with ephedra?
MI, HTN, Sympathomimetics, MAOIs
What are the CNS side effects associated with ephedra?
Stroke, seizure, anxiety
What is Echinacea taken for?
Enhance immune function, URI prevention and treatment, UTIs
What is Ephedra taken for?
Diet aid, Stimulant, Bronchodilator
What is the most serious side effect associated with echinacea?
Hepatotoxicity
What patients should not take echinacea?
immunocompromised (AIDs, Cancer)
Which drug can potentiate Parkinsonian symptoms?
a) St. John’s Wart
b) Saw Palmetto
c) Valerian
d) Kava
e) non of the above
d
Which drug causes increased metabolism of many of the drugs we use?
a) Ephedra
b) St. John’s Wart
c) Ginseng
d) a and b
e) none of the above
b
Which drugs following leads to increased sedative effects if not stopped pre-operatively?
a) Valerian
b) Saw Palmetto
c) Kava
d) a and b
e) a and c
e
Which of the following can cause hepatotoxicity?
a) Kava
b) St. John’s Wart
c) Echinacea
d) a and b
e) a and c
e
Which of the following drugs’ indications for use include: osteoarthritis
a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin
b
Which of the following drugs is indicated for use for: CAD, HTN, cholesterol, and as an anti-inflammatory
a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin
a
Which of the following inhibits serotonin, NE, epi, and dopamine re-uptake?
a) Garlic
b) Ephedra
c) St. John’s Wart
d) Kava
c
Which of the following is an antioxidant whose indications for use include: heart failure, reduce BP, Parkinson’s, and cancer?
a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin
d
Which of the following is taken to enhance energy levels?
a) Ephedra
b) Ginseng
c) Ginkgo
d) Saw Palmetto
b
Which of the following must be used with caution with anti-coagulants/ anti-platelets?
a) Garlic
b) Ginger
c) Ginko
d) Ginseng
e) all of the above
e
Which of the following must be used with caution with anti-coagulants/ anti-platelets?
a) Saw Palmetto
b) Vitamin E
c) Gingeng
d) Ginger
e) all of the above
E
Which should be avoided in pts w/seizure disorder?
a) Ginseng
b) Ginkgo
c) Kava
d) St. John’s Wart
b
Which types of drugs interact with ephedra?
MAOIs and sympathomimetics
