Lecture 07_Spring

Question 1

Garlic is commonly used to lower blood pressure and lipids. Does it need to be stopped before surgery? If so, how far in advance and why?

Answer 1

Yes b/c it is an anti-platelet drug and will cause increased bleeding. It must be stopped 1-2 weeks before surgery

Question 2

Grapefruit juice has which of the following effects on the serum concentration of intraop drugs?

a) it induces CYP enzymes and increases drug metabolism
b) it inhibits CYP enzyme and decreases drug metabolism
c) it has no effect on CYP enzymes

Answer 2

b

Question 3

Indications for use of which drug include: jet lag and insomnia?

a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin

Answer 3

e

Question 4

Indications for use of which drug include: stroke,MI, and artherosclerosis?

a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin

Answer 4

c

Question 5

True or False. Garlic acts as anti-platelet?

Answer 5

TRUE

Question 6

What are the cardiac side effects associated with ephedra?

Answer 6

MI, HTN, Sympathomimetics, MAOIs

Question 7

What are the CNS side effects associated with ephedra?

Answer 7

Stroke, seizure, anxiety

Question 8

What is Echinacea taken for?

Answer 8

Enhance immune function, URI prevention and treatment, UTIs

Question 9

What is Ephedra taken for?

Answer 9

Diet aid, Stimulant, Bronchodilator

Question 10

What is the most serious side effect associated with echinacea?

Answer 10

Hepatotoxicity

Question 11

What patients should not take echinacea?

Answer 11

immunocompromised (AIDs, Cancer)

Question 12

Which drug can potentiate Parkinsonian symptoms?

a) St. John’s Wart
b) Saw Palmetto
c) Valerian
d) Kava
e) non of the above

Answer 12

d

Question 13

Which drug causes increased metabolism of many of the drugs we use?

a) Ephedra
b) St. John’s Wart
c) Ginseng
d) a and b
e) none of the above

Answer 13

b

Question 14

Which drugs following leads to increased sedative effects if not stopped pre-operatively?

a) Valerian
b) Saw Palmetto
c) Kava
d) a and b
e) a and c

Answer 14

e

Question 15

Which of the following can cause hepatotoxicity?

a) Kava
b) St. John’s Wart
c) Echinacea
d) a and b
e) a and c

Answer 15

e

Question 16

Which of the following drugs’ indications for use include: osteoarthritis

a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin

Answer 16

b

Question 17

Which of the following drugs is indicated for use for: CAD, HTN, cholesterol, and as an anti-inflammatory

a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin

Answer 17

a

Question 18

Which of the following inhibits serotonin, NE, epi, and dopamine re-uptake?

a) Garlic
b) Ephedra
c) St. John’s Wart
d) Kava

Answer 18

c

Question 19

Which of the following is an antioxidant whose indications for use include: heart failure, reduce BP, Parkinson’s, and cancer?

a) fish oil
b) Glucosamine
c) Vitamin E
d) Coenzyme Q10
e) Melatonin

Answer 19

d

Question 20

Which of the following is taken to enhance energy levels?

a) Ephedra
b) Ginseng
c) Ginkgo
d) Saw Palmetto

Answer 20

b

Question 21

Which of the following must be used with caution with anti-coagulants/ anti-platelets?

a) Garlic
b) Ginger
c) Ginko
d) Ginseng
e) all of the above

Answer 21

e

Question 22

Which of the following must be used with caution with anti-coagulants/ anti-platelets?

a) Saw Palmetto
b) Vitamin E
c) Gingeng
d) Ginger
e) all of the above

Answer 22

E

Question 23

Which should be avoided in pts w/seizure disorder?

a) Ginseng
b) Ginkgo
c) Kava
d) St. John’s Wart

Answer 23

b

Question 24

Which types of drugs interact with ephedra?

Answer 24

MAOIs and sympathomimetics