LECT DSA - Historical Review of OMM Research Flashcards
What is the AOA definition of OMM research?
Investigator states the relevance of proprosed project to osteopathic philosophy and principles, theories, mechanisms or practice
Who was the pioneer career osteopathic researcher, serving as director of AT Still Research Institute and AOA researcher?
Dr. Louisa Burns
What was Dr. Louisa Burns research in?
Viscerosomatic reflexes
Who studied with Dr. Louisa Burns and reproduced/validated her experiments?
Dr. Wilbur Cole
Who pioneered research in somatic dysfunctions/”osteopathic lesions”?
Dr. J.S. Denslow
What did Dr. Denslow’s research consist of?
EMG/palpation correlation: documented spinal muscle reflex changes in areas of “osteopathic lesions”
Which DO was an important proponent of standard terminology?
Dr. J.S. Denslow
What did Dr. I.M. Korr’s research consist of?
Galvanic skin resistance as a result of disturbances in autonomic fxn in areas associated w/ palpatory findings and SD
Axoplasmic flow of nutrients and trophic fxn of nerves (movement of nutrients and ptns from cell body to cell body)
Who did Dr. Korr study facilitation of spinal cord with?
Dr. Denslow
What is sympathicotonia?
Heightened sympathetic tone
Increased autonomic outflow
(pathologic)
Who was a big proponent of DO-patient interaction along with OMT as research paradigm?
Dr. I.M. Korr
Who is referred to as the “Second Great philosopher of Osteopathic Medicine”?
Dr. I.M. Korr
Korr took still’s ____ foundation and added ___ fxn to it.
Korr took still’s anatomical foundation and added physiological fxn to it.
What type of research was Dr. William Johnston involved in?
Reliability studies
Validity studies
Viscerosomatic reflexes
What were the MD vs DO mortality comparisons during the Spanish Influenza epidemic of 1918?
Overall mortality: MD - 5%, DO - 0.25%
Mortality w/ PNA complication: MD - 30-60%, DO - 10%
What are the MD+DO vs DO only comparisons during 1932 at Unit II L.A. County Osteopathic Hospital?
Mortality: MD/DO - 9.7%, DO - 5.53%
Average Length of Stay (LOS): MD/DO - 16 days, DO - 9.7 days
Coroner’s cases: Both MD and DO - 14%
In Dr. Anderson’s “A Comparison of Osteopathic Spinal Manipulation with Standard Care for Patients with Low Back Pain” in 1999, what were the subject criteria?
Backpain duration: At least 3 weeks, less than 6 mo
Age: 20-59
Standard care vs Osteopathic manipulation+standard care
In Dr. Anderson’s “A Comparison of Osteopathic Spinal Manipulation with Standard Care for Patients with Low Back Pain” in 1999, what was the comparison of medications given for DOs and MDs?
OMT+PT+meds Significantly lower
- NSAIDS: 24%
- Muscle relaxers: 6%
- PT: 0.2%
MD+PT+Meds
- NSAIDS: 54%
- M. Relaxers: 25%
- PT: 2.6%
In Dr. Anderson’s “A Comparison of Osteopathic Spinal Manipulation with Standard Care for Patients with Low Back Pain” in 1999, what were the outcomes of DO vs MD patients?
Outcomes were the sasme except the osteopathic group required less medication and PT (cheaper)
In general, what are the outcomes for OMT in inflammatory disorders such as pancreatitis and ankle sprains?
Pancreatitis - Decreased LOS, analgesic use
Ankle sprain - decreased edema, pain, increased ROM
In general, what are the outcomes for OMT in PNA?
Decreased LOS
In general, what are the outcomes for OMT in pediatric otitis media?
Fewer surgical procedures
Higher avg surgery-free months
Increased frequency of normal tympanograms
In general, what were the results of Dr. Lisa Hodge’s Dog Lab w/ Lymphatic Pump Treatment?
Increased flow of lymph in the thoracic duct
Increased # of circulating Leukocytes
Abdominal pump showed greater increase than thoracic pump
In the Dog Lab With LPT, what cells have been measured increased in lymph?
Lymphocytes: CD4, CD8, IgA B cells IgG B cells
Neutrophils
Monocytes
In lymphatic pump treatment, how long does it take go get maximum release of cells, cytokines, and proteins from the nodes?
2 minutes
What substance influences contraction of lymph vessels? Stimulated by what?
NO, release stimulated by inflammation
What were the 3 research groups of rats studied in LPT in disease states? What were they infected with?
Control - Under anesthesia
Sham Treatment - Light touch, anesthesia
LPT - Anesthesia
Streptococcus pneumoniae
What were the results of LPT in disease states?
Control/sham groups: steady increase of bacterial in bronchial washings
LPT: steady decline of bacteria after 2-3 treatments , decreased immune cell concentration over time
In LPT in diseased state, what cytokines/cells/serum markers showed no difference b/w control and treatment group?
Alveolar leukocytes, IL-1B, CRP, TNF-a, MCP-1, CBC
What chemokines showed an increased concentration in LPT in diseased states? What does this support?
SP-D, IL-6, IL-17, IL-12, enhanced production of NO2 and IL-6 by alveolar macrophages
Supports clinical use of LPT in treating pneumococcal PNA
What patient population can LPT help for immune function?
Pts that are immobile
What were the results of the the LPT experiment that injected rats with tumor cells?
LPT group had decreased # of tumors
40% tumor reduction in lungs
Increase of every cell type in lungs (antitumor and NK cells)
Increased IL-2
