Lect 8- Atherosclerotic CV Disease Flashcards
what contributes to ASCVD risk?
age (risk increases with time), sedentary lifestyle, suboptimal diet, tobacco/ EtOH, dyslipidemia, excessive weight, HTN
atherosclerotic cardiovascular disease (ASCVD)
• A lot of times will begin with CAD (50% obstruction of coronary artery)
○ Chest pain
• Chronic stable angina and acute coronary syndrome
• Carotid disease= typically leads to stroke/ TIA
• Peripheral vascular disease
“silent” ASCVD continuum
> 50% obstruction of coronary artery, chronic stable angina, peripheral artery disease
“overt/ Hard” ASCVD continuum
acute coronary syndrome, stroke/ TIA
primary prevention
measures taken to prevent onset of disease by controlling BP, dyslipidemia, tobacco abuse, lifestyle factors, and POTENTIALLY initiating antithrombotic therapy for high-risk pts
• Consider aspirin but not if there is low risk
○ Greater risk of bleeding than preventing CVD
○ Only use if risk of CV events is greater than risk for GI bleed
secondary prevention
measures taken to prevent recurrence/progression of diagnosed ASCVD by controlling BP, dyslipidemia, tobacco abuse, lifestyle factors, and initiating antithrombotic therapy for ALL PATIENTS w/o C/I
what is your thumb on the hand memory aid?
HTN
do they have it and are they on any drugs for it
what is your pointer finger on the hand memory aid?
dyslipidemia
what is your middle finger on the hand memory aid?
diabetes
what is your ring finger on the hand memory aid?
lifestyle
what is your pinky on the hand memory aid?
antithrombotic
aspirin, plavix, warfarin, etc
atheroembolic event
plaque rupture
coronary artery disease (CAD)
ARTERIAL sclerosis leads to plaque rupture
use antiplatelets
atheroembolic stroke
ARTERIAL sclerosis leads to plaque rupture which blocks brain blood flow
use antiplatelets
cardioembolic stroke
abnormal flow/inflammation/ endothelial dysfunction leads to activation of clotting factors
use anticoags for atrial fibillation
