Lect 7 Flashcards

1
Q

HD complications

A
  1. hypotension
  2. muscle cramps
  3. pruritis
  4. N/V
  5. HA
  6. chest pain
  7. fever/ chills
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2
Q

causes of hypotension in HD

A

hypovolemia, anti-HTN meds or meals prior to HD, target dry weight set too low, acetate dialysis solution base

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3
Q

acute management of hypotension in HD

A

Trendelenburg position
decrease ultrafiltration rate
fluid bolus: 100-200 mL IV NS

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4
Q

pharm tx for hypotension

A
  • midodrine before HD
  • levocarnitine after HD
  • fludrocortisone before HD
  • sertraline DAILY
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5
Q

muscle cramps causes in HD

A

dehydration

Na in dialysate too low

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6
Q

acute management of muscle cramps in HD

A

fluid bolus

NS 100-200 mL IV

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7
Q

prevention of muscle cramps

A

dialysate sodium > serum Na

vit E at bedtime

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8
Q

vascular access complications

A

dec blood flow through the access site over days-weeks (less than 300 mL/min)

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9
Q

vascular access complications

A

dec blood flow through the access site over days-weeks (

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10
Q

prevention and treatment of intrinsic thrombosis in catheter

A

saline, heparin, alteplase locks to prevent

saline flush or alteplase to treat

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11
Q

prevention and treatment of extrinsic thrombosis in catheter

A

replacement of catheter

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12
Q

PD complications

A
  1. mechanical
  2. pain
  3. metabolic complications
  4. peritoneal memb damage
  5. infections (peritonitis; exit-site)
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13
Q

peritonitis is higher in ___

A

CAPD than APD

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14
Q

which org is predominant in peritonitis?

A

Staph epidermidis (G(+))

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15
Q

when do you start empiric abx in peritonitis pts?

A

cloudy fluid and/or abd pain and/or fever
WBC >100
*intraperitoneal admin preferred
(in asymptomatic pts w/ cloudy effluent, just wait for differential/culture return)

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16
Q

what is the empiric tx for G(+) peritonitis?

A

vanc

17
Q

what is the empiric tx for G(-) peritonitis?

A

aminoglycoside, ceftazidime, cefepime, carbapenem, FQ (if local susceptibilities) or aztreonam (PCN/ Ceph allergy)

18
Q

enterococcus

A

ampicillin

21 days

19
Q

MSSA

A

nafcillin or oxacillin

21 days

20
Q

MRSA

A

vanc or clindamycin

21 days

21
Q

single org other than Pseudomonas or Stenotrophomonas

A

start tx based on sensitivities

14 days!!

22
Q

Pseudomonas

A

can D/C vanc
antipseudomonal tx
21 days

23
Q

Stenotrophomonas

A

Bactrim

21 days

24
Q

multiple G(-) and/or anaerobes

A

D/C vanc
metronidazole
21 days

25
Q

culture negative

A

measure clinical improvement at 96 hours
if improved= narrow tx
no improvement= repeat cultures and gram stain; consider removal of catheter

26
Q

fungal org

A

newer agents in combo (fluconazole & flucytosine)

27
Q

fungal org

A

newer agents in combo (fluconazole & flucytosine)

28
Q

when should you consider removal of cath from fungal org?

A

pt does not respond after 4-7 days of tx → remove catheter and continue tx for extra 7 days → no response then continue tx for 4-6 weeks