Lec4 Flashcards
In the upper respiratory tract of kids
Diphtheria toxin
Diphtheria toxin Produced by
Corynebacterium diphtheriae
Tetanus neurotoxin (tetanospasmin) Produced by
anaerobe Clostridium tetani
after a wound injury contaminated with soil carrying its spores.
Tetanus neurotoxin
Produced by the anaerobe Clostridium tetani
Tetanus neurotoxin (tetanospasmin)
Inside canned foods under anaerobic conditions causing botulism
Botulinum neurotoxin (BONT)
is an adenylate cyclase that raises the cAMP concentration within the cell, resulting in loss of chloride ions and water and consequent edema formation in the tissue.
Edema factor
is a protease that cleaves the phosphokinase. This stops cell growth and consequent cell death.
Lethal factor
binds to receptors and forms pores in the human cell membrane that allow edema factor and lethal factor to enter.
Protective antigen
Occurs to farmers and among workers in textile or tanning industries who handle contaminated animal wool, hair, and hides.
Inhalation anthrax
Inhalation anthrax death percentage
95%
Gastrointestinal anthrax death percentage
50%
Cutaneous anthrax percentage
20%
consists of extract from a nondisease-causing strain of B.anthracis.
BioThrax vaccine
Staphylococcal enterotoxin poisoning within …… hours after ingestion.
1 to 6 hours
Staphylococcal enterotoxin superantigen acts on the lymphoid cells lining the …….
small intestine.
Causes the rash characteristic of scarlet fever.
Erythrogenic toxin Produced by St: Pyogenes.
This is a pore-forming exotoxin produced by MRSA to destroy the WBCs.
PV leukocidin
wesultimgyin the detachment of the superficial layers of the skin causing scalded skin syndrome.
Epidermolytic toxin (Exfoliatin)
is a lecithinase that hydrolyzes lecithin in the cell membrane, resulting in destruction of the membrane and widespread cell death.
Alpha toxin (Clostridium perfringens toxins )
is an enterotoxin that causes watery diarrhea.
Exotoxin A (Clostridium difficile toxins)
