Lec 8 Flashcards
Where is aq humor produced?
CB epith
What enzymes control aq humorproduction?
Carbonic anhydrase, Na/K-dependent ATPase
Describe: conventional route of aq humor outflow
aq humor passes through TM into Schlemm’s canal. Exits through collector channels into venous system; 70%+ of outflow
Describe: Unconventional route of aq humor outflow
Aq humor passes through uvealscleral pathway: through iris root uveal meshwork and anterior face of ciliary muscle –> through suprachoroidal space and out through slera; 30% or less of outflow
What is the most significant factor in the etiology of increased IOP?
interference with aqueous outflow
T/F: Prostaglandins increase outflow; Carbonic anhydrase inhibit production of aq humor
True
What % of pts dev glauc despite normal IOP?
30%
What is the diameter of the circular zone of applanation?
3.06 mm
What is the area of applanation?
7.3542 mm^2
Applanation tonometry has what standard dev of error?
+/- 0.5 mm Hg
What assumptions did Hans Goldmann make when devising his tonometer?
avg corneal thickness of 20 microns, resistance to deformation is cancelled out by surface tension generated when the area applanated has a diameter of 3.06mm
GAT: 1 g of force needed to flatten an an area equal to what? which means the diameter is what?
7.3542 mm^2, 3.06 mm
What are indications for punctal occlusion?
Preg, very young, HTN, when using multiple drops (so pt doesn’t taste it), very dark brown eyes
Drops have been instilled. What happens every time a pt blinks?
meds go into the lac canal/sac and increase systemic absorpton
Fluress vs Flurox. Which has benoxinate?
Fluress has benoxinate