Lec-2 Pharmacokinetics Flashcards
1
Q
Pharmacokinetics
A
-is how the body deals with the drug
- The quantitative analysis of the relationship between the dose of a drug and the ensuing changes in drug concentration in the blood and other tissues
2
Q
Important phases of Pharmacokinetics
A
A.D.M.E
Absorption
distribution
Metabolism
Excretion
3
Q
Absorption
A
- Many factors influence it- especially route of administration
4
Q
Intraveinous (iv) route
A
bypasses most barriers to get to plasma/ central compartment
5
Q
All drugs eventually interact with?
A
The plasma also called the central compartments
6
Q
Diffusion can go…
A
both ways between compartments
(muscle <—> plasma, gut <—> plasma)
7
Q
How do drugs move through the cellular barriers
A
Passive and active transport
8
Q
what is passive transport
A
9
Q
what is active transport
A
10
Q
A
