Lec 16: Root and Peripheral Nerve Lesions

Question 1

A single Schwann cell myelinates how many axons?

A. 1
B. 5
C. >10
D. >50
E. It does not produce myelin

Answer 1

A. 1:1 ratio

Oligodendrocytes on the other hand myelinates more than one axon.

Question 2

In the damage process, permanent peripheral nerve damage sets in

A. demyelination
B. compression
C. disconnection
D. degeneration
E. AOTA

Answer 2

C. disconnection

Question 3

Neuronal degeneration occurs in the following EXCEPT

A. amyloidosis
B. motor neuron disease
C. cadmium poisoning
D. poliomyelitis
E. NOTA

Answer 3

E. NOTA

Question 4

T/F: Neuronal recovery in neuronal degeneration is typically delayed and incomplete.

Answer 4

F

There is no possibility of recovery in neuronal degeration.

Delayed and incomplete recovery may be seen in AXONAL DEGENERATION.

Question 5

True of myelin EXCEPT

A. good insulator and facilitates conduction
B. uniform and thinly laid myelin for faster conduction
C. myelinated nerve conducts 50x faster
D. myelin also serves as a protector
E. NOTA

Answer 5

B.

Thicker myelin means faster conduction.

Question 6

T/F: Surrounding Schwann cells can give myelin sheath to demyelinated axons.

Answer 6

T

Question 7

Enumerate two cranial nerves which are not peripheral nerves.

Answer 7

I and II

They are outpouching of the telencephalon / cerebrum.

Question 8

The following are negative symptoms of neuropathy EXCEPT

A. weakness
B. hypotonia
C. areflexia
D. paresthesia
E. NOTA

Answer 8

D.

Paresthesia is a positive symptom.

Question 9

ID: This is the treatment for hyperhidrosis.

Answer 9

botox

Question 10

The following is/are generalized neuropathy/ies.

A. diabetes mellitus
B. guillian-barre syndrome
C. neuralgia syndrome
D. A & B only
E. AOTA

Answer 10

C.

Neuralgia is a focal neuropathy.

Question 11

True of generalized neuropathies EXCEPT

A. distal nerves are affected first
B. sensory fibers are affected first
C. common in those with high protein and meat intake
D. common in those undegoing chemotherapy
E. NOTA

Answer 11

C.

They are common in vegetarians.

Question 12

ID: This is the most common form of generalized neuropathy.

Answer 12

diabetes mellitus

Question 13

ID: The accumulation of these two glucose metabolites leads to reduced nerve myoinositol.

Answer 13

sorbitol

fructose

Question 14

T/F: Guillain-Barre syndrome is a chronic, ascending, and progressive neuropathy.

Answer 14

F

It is ACUTE.

Question 15

ID: The common pathology in Guillain-Barre syndrome and variants is

Answer 15

demyelination

It is due to antibody attack on Schwann cells and myelin.