lec 16. membrane contact sites

Question 1

NPC1 and NPC2

Answer 1

proteins that facilitate the transfer of cholesterol from endosome -> lysosome -> ER for recycling

Question 2

membrane contact sites

Answer 2

close appositions between two organelles

Question 3

sarcoplasmic reticulum

Answer 3

ER in muscle cells which wraps around myofibre and associated with their plasma membrane. As the muscle cell interprets action potentials, it gets a quick release of Ca+ from the SR through ryanodine receptors, so that is can contract